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WormBase Tree Display for Strain: WBStrain00004602

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Name Class

WBStrain00004602StatusLive
Genotype
Public_nameCB4856
ContainsGene
Variation (243344)
PropertiesCGC_received31 Jan 1991 00:00:00
PhenotypeWBPhenotype:0000135Paper_evidenceWBPaper00060196
Curator_confirmedWBPerson712
Remarkexpresses higher levels of cdr-6Paper_evidenceWBPaper00060196
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00005358Paper_evidenceWBPaper00060196
Curator_confirmedWBPerson712
WBPhenotype:0000154Paper_evidenceWBPaper00040740
Curator_confirmedWBPerson712
RemarkThe median brood size of CB4856 was about half that of N2.Paper_evidenceWBPaper00040740
Curator_confirmedWBPerson712
WBPhenotype:0000660Paper_evidenceWBPaper00005511
WBPaper00032342
Curator_confirmedWBPerson2021
WBPerson712
RemarkSocial feeders aggregated within 20 min of being placed on a fresh food source. In the absence of food, wild-type social animals failed to aggregate at any densityPaper_evidenceWBPaper00005511
Curator_confirmedWBPerson2021
Phenotype_assayTreatmentAnimals were grown on a lawn of E. coli constitutively expressing GFP, in which the fluorescent intensity in the outer 40% of the lawn (border) is w35% brighter than in the inner 60% (center), suggesting differences in bacterial density.Paper_evidenceWBPaper00032342
Curator_confirmedWBPerson712
WBPhenotype:0000997Paper_evidenceWBPaper00035614
Curator_confirmedWBPerson2021
RemarkThe strain CB4856 showed a strong tendency to migrate toward the cold area of the temperature gradient, regardless of the conditioning temperaturePaper_evidenceWBPaper00035614
Curator_confirmedWBPerson2021
WBPhenotype:0001013Paper_evidenceWBPaper00032501
Curator_confirmedWBPerson2021
RemarkUpon exposure to Pseudomonas aeruginosa strain PA14, the mean time to 50% lethality (LT50) for CB4856 was shorter than that for N2Paper_evidenceWBPaper00032501
Curator_confirmedWBPerson2021
WBPhenotype:0001014Paper_evidenceWBPaper00040740
Curator_confirmedWBPerson712
RemarkS. avermitilis significantly reduced the brood size and induced uncoordinated movement in N2 animals; however, in the presence of S. avermitilis, the median brood size of CB4856 was about five times higher than N2.Paper_evidenceWBPaper00040740
Curator_confirmedWBPerson712
WBPhenotype:0001420Paper_evidenceWBPaper00029153
Curator_confirmedWBPerson712
RemarkAnimals are able to grow on lawns of Yersinia pseudotuberculosis.Paper_evidenceWBPaper00029153
Curator_confirmedWBPerson712
WBPhenotype:0001749Paper_evidenceWBPaper00060196
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00005358Paper_evidenceWBPaper00060196
Curator_confirmedWBPerson712
WBPhenotype:0001764Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
RemarkStrains AB1, CB4853, and CB4856 are essentially unresponsive to CO2 compared to N2 controlPaper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000057PATO:0000460Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
Phenotype_assayTreatment10% CO2Paper_evidenceWBPaper00031936
Curator_confirmedWBPerson2021
WBPhenotype:0001819Paper_evidenceWBPaper00032501
Curator_confirmedWBPerson2021
RemarkCB4856 animals tend to show increased accumulation of PA14-GFP in the standard slow-killing assay as compared with N2Paper_evidenceWBPaper00032501
Curator_confirmedWBPerson2021
WBPhenotype:0002048Paper_evidenceWBPaper00040740
Curator_confirmedWBPerson712
RemarkThe Hawaiian wild isolate of C. elegans, CB4856, was resistant to abamectin, while the laboratory strain,N2, was sensitive under identical conditions. | A 4.5-kb N2 genomic fragment containing two genes, including glc-1, significantly reduced abamectin resistance of CB4856. | Crossing CB4856 with a glc-1(pk54) mutant strain, resulted in F1 progeny resistant to abamectin.Paper_evidenceWBPaper00040740
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00003970Paper_evidenceWBPaper00040740
Curator_confirmedWBPerson712
WBPhenotype:0002053Paper_evidenceWBPaper00040740
Curator_confirmedWBPerson712
RemarkThe Hawaiian wild isolate of C. elegans, CB4856, was resistant to ivermectin, while the laboratory strain,N2, was sensitive under identical conditions.Paper_evidenceWBPaper00040740
Curator_confirmedWBPerson712
Affected_byMoleculeWBMol:00002786Paper_evidenceWBPaper00040740
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000147Paper_evidenceWBPaper00059614
Curator_confirmedWBPerson712
RemarkPost-dauer adults displayed a significant reduction in brood size relative to control adults, which is similar to effects in N2.Paper_evidenceWBPaper00059614
Curator_confirmedWBPerson712
WBPhenotype:0001612Paper_evidenceWBPaper00035666
Curator_confirmedWBPerson2021
RemarkStrain does not differ significantly from N2 in its response to ethanolPaper_evidenceWBPaper00035666
Curator_confirmedWBPerson2021
WBPhenotype:0001747Paper_evidenceWBPaper00031911
Curator_confirmedWBPerson712
RemarkHermaphrodites displayed a sensitivity similar to N2 hermaphrodites to supplemental zinc.Paper_evidenceWBPaper00031911
Curator_confirmedWBPerson712
EQ_annotationsMolecule_affectedWBMol:00005064PATO:0000460Paper_evidenceWBPaper00031911
Curator_confirmedWBPerson712
Phenotype_assayTreatmentAnimals were cultured on Nobel agar minimal media (NAMM) with supplemental zinc sulfate starting at the egg stage, and development was monitored daily.Paper_evidenceWBPaper00031911
Curator_confirmedWBPerson712
Temperature20Paper_evidenceWBPaper00031911
Curator_confirmedWBPerson712
LocationCGC
CB
Remark (25)
Reference (106)
SpeciesCaenorhabditis elegans
Wild_isolate
IsolationGPS21.33-157.86
PlaceHawaii
LandscapeRural_garden
Substratepineapple_field
Sampled_byL. Hollen
Date01 Aug 1972 00:00:00