WormBase Tree Display for Strain: WBStrain00000276
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| WBStrain00000276 | Status | Live | ||
|---|---|---|---|---|
| Genotype | me8 X. | |||
| Public_name | AV51 | |||
| Contains | Variation | WBVar02154041 | ||
| Properties | Outcrossed | x4 | ||
| Mutagen | EMS | |||
| CGC_received | 16 Jun 1997 00:00:00 | |||
| Location | CGC | |||
| Made_by | WBPerson1547 | |||
| Remark | Homozygotes produce 10-15% XO male self progeny; nondisjuction is correlated with an increased frequency of achiasmate X chromosomes in oocyte nuclei, and an unaltered distribution of X chromosome crossovers. Heterozygotes produce 1-2% male self-progeny. Homozygotes (and XO hemizygotes) are slower growing than WT; reduced male mating efficiency. me8 disrupts the function of the cis-acting X chromosome meiotic pairing center. Molecular studies show that the me8 chromosome carries a terminal deletion that removes >70 kb from the left end of the X chromosome, including the endogenous telomere; further, a segment of chromosome V has been translocated to the left end of X, and a new telomere has been added de novo to the end of the translocated segment. | Inferred_automatically | From CGC strain data | |
| Reference | WBPaper00001924 | |||
| Species | Caenorhabditis elegans |
