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WormBase Tree Display for RNAi: WBRNAi00110140

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Name Class

WBRNAi00110140HomolHomol_homolY47G6A:RNAi
Sequence_infoPCR_productsjj_Y47G6A_247.f
InhibitsPredicted_geneY47G6A.10Inferred_automaticallyRNAi_primary
GeneWBGene00004978Inferred_automaticallyRNAi_primary
TranscriptY47G6A.10.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
InteractionWBInteraction000537472
WBInteraction000537474
ReferenceWBPaper00046902
PhenotypeWBPhenotype:0000136RemarkIn response to spg-7(RNAi): "Specifically, ATFS-1 bound the promoters of nuaf-1 and Y17G9B.5 (ECSIT), two NADH ubiquinone oxidoreductase assembly factors, and lpd-8 (NFU1), a Fe-S cluster biogenesis component (Figures 6A-6C). These genes were induced during mitochondrial stress* in an atfs-1-dependent manner (Figures 6D-6F), suggesting a role for ATFS-1 in OXPHOS complex assembly." *spg-7(RNAi)
EQ_annotationsGO_termGO:0034514PATO:0000460
Remark(Figures 6D-F) spg-7 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
MethodRNAi