WormBase Tree Display for RNAi: WBRNAi00094624
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| WBRNAi00094624 | Homol | Homol_homol | C07G2:RNAi | ||
|---|---|---|---|---|---|
| Sequence_info | DNA_text | ATGTCGGTCGTAACAACGACGAGCATGCAGTCGGATTCAAAAAAGCGCGTCCAATTGATGGGCGACACAACGTCTCCATTCAGTCTCGATACTCCAAACCCAAAATTAATGTTCACTCCACTTGATCTACCAACAACCGCTGAACTAATGCAACGATGTCTAGCAGTAAATCCATTCGAAGCAAAGTTCCGAGAAGCGAATCAAAAGATCAGTTCTGGAAGTATGCAACCAAATACATCAGGTGCAAATCAATCTCTTGAAGCTTTGGAAGCCAATGGAGGTTCACAATTTTCGGGAAGTAATGCCGGAACAATGTCGGATCTTTTATTGAAAATACCACAAGCATCACTTCAACATTCGCCTGGAATATTTTCAAATATGCTTCTAAATGCTGGAGATTCGGAGGGAACGACTCGAGAAAATCTGAAAACCGCGGACATTTCCAAATTGTTATCTGTGGCCGGTGACTTCTCGGCTCAAGCTCCACGAACTGCCGACGTTTTAAACGCGGTACTCGACATGCACTCTGATAGACTTCATACAATCAACTATTTGAATAATAAGCCTGATTTCTCGGCACTCCTTCGTTCTCCATCTTCTTCCGCACCCAATTCAGCATCTGTTCTTACGAATGCGATGGCTATTCCATCTACAAGTGGAGCACCTTTTCCTGGAACAACACTGCTTGTTCCTCCAAAAACTGTGAGCTCCTATCACTCACCACTTGGAGCATCATCACAACCTCCATCCACACAAAAATCACCAGCTGATGGAAGTTGGGATCATATAAACGGAGAAAAGCAGATCAAAAAGGAAATTCCATATTTTAATGATGATGCAATGATGTTGATGGAAAGGAGCAATATGTCATCTTCGGGATCTGATCAAGATCAGTCTGCAGATATGTCAAATGCTGGATCAACTGCTTCAACGAGTACTGGAAATCCAGTTGGACGTCCACAAAACGGTACACCTGGCCGTGGACGTGGTCGAGGAAGAAGCACAACAGCCGACATGCAACCCGACGAGAGGAGGAATACAATTCTCGAGAGAAATAAGGCTGCGGCTGTGAGATATCGTAAGAGGAAGAAGGAAGAACATGATGATATGATGGGAAGAGTTCAAGCAATGGAGGCTGAAAAGAATCAATTACTGACACAAAATCAAGTGCTGCGACGGGAACTCGAAAGGGTAACTGCGTTGCTTACTGAAAGAGAGTCACGATGCGTTTGTCTGAAAGGAGTTCCAATGAGTGATGAGCAGCACGCTGATCATCATCATCGAAACACGAATGGAATGTACTCTGGATCAGATATGCTCAATGGACTTGGACAAATCAACGGAATGCAACTGAAATTACCCAAACTCCAATGA | |||
| Experiment | Laboratory | AU | |||
| Date | 06 Apr 2012 00:00:00 | ||||
| Genotype | F35E12.5::GFP | ||||
| Treatment | Animals were exposed to 70 mM RPW-24, and grown with or without P. aeruginosa PA14. | ||||
| Temperature | 25 | ||||
| Delivered_by | Bacterial_feeding | ||||
| Inhibits | Predicted_gene | C07G2.2d | Inferred_automatically | RNAi_primary | |
| C07G2.2b | Inferred_automatically | RNAi_primary | |||
| C07G2.2c | Inferred_automatically | RNAi_primary | |||
| C07G2.2a | Inferred_automatically | RNAi_primary | |||
| Gene | WBGene00000223 | Inferred_automatically | RNAi_primary | ||
| Transcript | C07G2.2d.4 | Inferred_automatically | RNAi_primary | ||
| C07G2.2d.1 | Inferred_automatically | RNAi_primary | |||
| C07G2.2b.2 | Inferred_automatically | RNAi_primary | |||
| C07G2.2b.1 | Inferred_automatically | RNAi_primary | |||
| C07G2.2d.3 | Inferred_automatically | RNAi_primary | |||
| C07G2.2a.1 | Inferred_automatically | RNAi_primary | |||
| C07G2.2c.1 | Inferred_automatically | RNAi_primary | |||
| C07G2.2d.2 | Inferred_automatically | RNAi_primary | |||
| Species | Caenorhabditis elegans | ||||
| Reference | WBPaper00041211 | ||||
| Phenotype | WBPhenotype:0001278 | Remark | aft-7 RNAi was able to reduce the expression of F35E12.5::GFP in animals that were exposed to RPW-24. RPW-24 was shown to increase the expression of the F35E12.5::GFP transcriptional reporter and to stimulate the host immune response. This effect was seen when animals were either grown on OP50 or infected P. aeruginosa PA14. | ||
| Remark | RPW-24 is a molecule that protects C. elegans from bacterial infection by stimulating the host immune response. Addition of the small molecule RPW-24 was also shown to increase the expression of the F35E12.5::GFP transcriptional reporter. Exact sequence used for RNAi not stated by authors, spliced coding region sequence (07G2.2a) of gene used for curation. | ||||
| Method | RNAi |
