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WormBase Tree Display for RNAi: WBRNAi00093059

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Name Class

WBRNAi00093059HomolHomol_homolZK1058:RNAi
Sequence_infoPCR_productsjj_ZK1058.2
ExperimentLaboratoryNK
Date01 May 2013 00:00:00
Delivered_byBacterial_feeding
InhibitsPredicted_geneZK1058.2Inferred_automaticallyRNAi_primary
GeneWBGene00003930Inferred_automaticallyRNAi_primary
TranscriptZK1058.2.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00043893
PhenotypeWBPhenotype:0001652RemarkRNAi of pat-3 resulted in a dramatic reduction in invadopodia formation with dramatically reduced F-actin structure formation in the anchor cell.
RemarkExact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. To avoid embryonic lethality of pat-3 RNAi, synchronized L1-arrested larvae were grown for 5 h on regular OP50 bacteria in the absence of RNAi. These worms were then transferred to bacteria expressing pat-3 double-stranded RNA.
MethodRNAi