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WormBase Tree Display for RNAi: WBRNAi00090364

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Name Class

WBRNAi00090364HomolHomol_homolF52E10:RNAi
Sequence_infoPCR_productsjj_F52E10.1
ExperimentLaboratoryCC
Date15 Aug 2011 00:00:00
GenotypeccIs55 [unc-54::lacZ]; unc-51(e369)
Delivered_byBacterial_feeding
InhibitsPredicted_geneF52E10.1aInferred_automaticallyRNAi_primary
F52E10.1bInferred_automaticallyRNAi_primary
GeneWBGene00004745Inferred_automaticallyRNAi_primary
TranscriptF52E10.1b.1Inferred_automaticallyRNAi_primary
F52E10.1a.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
InteractionWBInteraction000519693
ReferenceWBPaper00040284
Phenotype_not_observedWBPhenotype:0001645RemarkThe unc-51(e369) mutation suppressed the RNAi-induced increase in protein degradation in muscle, as determined by LacZ staining, suggesting that the unc-51 signaling pathway (Autophagy pathway) is responsible for mediating the RNAi-induced increase in protein degradation in muscle.
Remark(Figure 4) sdc-1 RNAi
MethodRNAi