WormBase Tree Display for RNAi: WBRNAi00086076
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| WBRNAi00086076 | Homol | Homol_homol | F10E9:RNAi | ||
|---|---|---|---|---|---|
| Sequence_info | PCR_product | WBPaper00005739:F10E9_1.1 | |||
| Experiment | Laboratory | TH | |||
| Date | 04 Feb 2003 00:00:00 | ||||
| Treatment | GFP-alpha-tubulin used as marker. | ||||
| Delivered_by | Injection | ||||
| Inhibits | Predicted_gene | F10E9.8 | Inferred_automatically | RNAi_primary | |
| Gene | WBGene00004726 | Inferred_automatically | RNAi_primary | ||
| Transcript | F10E9.8.1 | Inferred_automatically | RNAi_primary | ||
| Species | Caenorhabditis elegans | ||||
| Reference | WBPaper00005739 | ||||
| Phenotype | WBPhenotype:0001903 | Remark | Centrosome duplication fails prior to the second mitotic division in sas-4(RNAi) embryos. In addition authors show that centriolar SAS-4 levels determine centrosome size. In all sas-4((RNAi) embryos microtubule dynamics and spindle assembly were identical to wild-type during the first mitotic division. However as sas-4(RNAi) embryos entered their second division, each daughter cell assembled only a single centrosomal microtubule aster. These single asters increased normally in size as the cells entered mitosis,and monopolar spindles were formed. | ||
| Method | RNAi |
