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WBPicture0000014049DescriptionFigure 2. A TCER-1::GFP fusion protein is widely expressed and rescues the shortened lifespan of tcer-1; glp-1 mutants. (A-C) tcer-1 expression in adult somatic tissues. TCER-1::GFP is expressed in nuclei of adult neurons ('n', head neurons shown by arrow in (A)), hypodermis ('h', (B)), muscles ('m', arrow in (C)), and intestinal cells ('i', arrowhead in (C)). The asterisk in (A) indicates expression of the co-injection marker, Podr1::RFP, in olfactory neurons. (D) Rescue of the shortened lifespan of tcer-1(2); glp-1(2) mutant by the TCER-1::GFP fusion protein (tcer-1 OE). glp1(2): m = 31.160.7, n = 204/241; tcer-1(2); glp-1(2): m = 23.460.5, n = 81/119, P vs. glp-1(2),0.0001; tcer-1(2); glp-1(2); tcer-1 OE: m = 32.460.3, n = 111/116, P vs. glp-1(2) = 0.5, P vs. tcer-1(2); glp-1(2),0.0001; tcer-1(2): m = 19.160.2, n = 50/64. See Table S1. C for additional trials of this experiment.
NameFigE.jpg
DepictExpr_patternExpr12818
AnatomyWBbt:0003675
WBbt:0003679
WBbt:0005792
WBbt:0007846
Cellular_componentGO:0005634
GO:0005737
Life_stageWBls:0000002
AcknowledgmentTemplateReprinted from <Journal_URL>, <Article_URL>. <Publisher_URL> <Publication_year>.
Publication_year2009
Article_URLDOIid10.1371/journal.pgen.1000639
Journal_URLPLoSGenetics
Publisher_URLPLoS
ReferenceWBPaper00035189