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WBPicture0000011632 | Description | FIG. 4. Localization of UNC-76 and UNC-76::b-galactosidase fusion proteins. Anterior is to the left, and dorsal is at the top. (A) UNC-76 protein in a wild-type adult is visible in the nerve ring (nr), ventral cord (vnc), dorsal cord (dc), and dorsal and ventral sublateral process tracts (arrows). UNC-76 protein in a wild-type adult (B) is more abundant than in an unc-76(ev424) mutant adult (C). (D) Dorsal region of a wild-type adult just anterior to the vulva. Staining is visible in the dorsal nerve cord (dc), dorsal sublateral tracts (sl), a left lateral tract (ll), and two motor commissures (c). (E) Midbody region of a wild-type adult. Staining is visible in cell bodies of PVDR, PDER, HSNR, and CANR as well as the dorsal (dc) and ventral (vnc) nerve cords, several longitudinal process tracts (arrowheads), and the circumferentially directed HSN axon (arrow). UNC-76 staining near the midbody region of L2 (F) and adult (G) ventral nerve cords and the corresponding nuclei visualized by diamidinophenolindole (I and J). (H) An UNC-86::UNC-76::b-galactosidase fusion protein encoded by p86/76-1 is localized to axons (arrow) as well as cell bodies (arrowheads) in a small set of neurons in the head of an adult stained with anti-b-galactosidase antibodies. (K) The equivalent UNC-86::b-galactosidase fusion protein lacking UNC-76 sequences (encoded by p86-L1) is confined primarily to cell bodies (arrowheads). Cell identities in H and K were not determined. [Bars = 50 um (A-C, E, H, and K) and 10 um (D, F, G, I, and J).] | |||
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Name | FigD.jpg | ||||
Depict | Expr_pattern | Expr1621 | |||
Anatomy | WBbt:0004088 | ||||
WBbt:0004382 | |||||
WBbt:0004757 | |||||
WBbt:0004947 | |||||
WBbt:0005829 | |||||
WBbt:0006749 | |||||
WBbt:0006750 | |||||
WBbt:0006751 | |||||
WBbt:0006830 | |||||
Cellular_component | GO:0030424 | ||||
GO:0044297 | |||||
Acknowledgment | Template | Reprinted with permission from <Journal_URL> <Article_URL>. Copyright (<Publication_year>), <Publisher_URL>. | |||
Publication_year | 1997 | ||||
Article_URL | DOI | id | 10.1073/pnas.94.7.3414 | ||
Journal_URL | ProcNatlAcadSciUSA | ||||
Publisher_URL | NationalAcademyofSciencesUSA | ||||
Reference | WBPaper00002751 |