WormBase Tree Display for Picture: WBPicture0000011141

WBPicture0000011141 Description: Figure 3. UNC-31 is expressed in neurons and is enriched at synapses. A, Confocal image of an adult hermaphrodite expressing GFP under the unc-31 promoter (oxEx608[Punc-31:GFP]). Expression of unc-31 is pan-neuronal with additional expression in the spermatheca and vulval muscles. Anterior is left. B, Confocal image of the ventral surface of an adult hermaphrodite expressing GFP under the unc-31 promoter. Expression is observed in the vulval muscles VM1 and VM2. Expression is also seen in the UV1 cells. C, Confocal images of unc-31(e928) oxEx608[UNC-31:GFP]. UNC-31:GFP protein localizes to the synaptic-rich region of the nerve ring as well as the dorsal and ventral nerve cords. GFP expression inside the dashed circle around the posterior bulb of the pharynx can be disregarded because it arises from the coinjection marker (Pmyo-2:HIS::GFP). Additional diffuse expression of the coinjection marker can also be seen in the isthmus of the pharynx. D, Subcellular localization of UNC-31:GFP in the SAB neurons of the head. Punctate expression as well as colocalization with the synaptic vesicle marker synaptobrevin (a-SNB-1) indicate that UNC-31 is localized to synaptic terminals, reported previously by Charlie et al. (2006).
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  Acknowledgment: Template: WormBase thanks <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>.
    Publication_year: 2007
    Article_URL: DOI id 10.1523/JNEUROSCI.1466-07.2007
    Journal_URL: TheJournalofNeuroscience
    Publisher_URL: SocietyofNeuroscience
  Reference: WBPaper00030754