WormBase Tree Display for Picture: WBPicture0000009762

WBPicture0000009762 Description: Figure 3. RSD-3 Is Expressed in Coelomocytes and Is Homologous to the Human Protein Enthoprotin. (A) rsd-3 is highly expressed in endocytic cells. A transgenic animal with GFP fused to exon V of the rsd-3 gene shows high expression in the coelomocytes. An identical expression pattern was observed for transgenic animals in which GFP was fused to the end of the protein (data not shown). (i) fluorescent image, showing RSD-3 expression. (ii) Nomarski image of the same area of the animal. (iii) Merged image.(B) Alignment of C. elegans RSD-3 and human Enthoprotin. The ENTH domain is shaded grey and residues highlighted in red (high consensus), blue (low consensus), or black (no consensus). The two proteins show 37% identity and 51% similarity over the entire length of RSD-3.(C) A rooted tree showing the evolutionary relationship of C. elegans and human ENTH domain-containing proteins. Enthoprotin and RSD-3 do not cluster together with ENTH-domain proteins that act in the clathrin-endocytosis pathway. Characterized proteins are named, all other ENTH domain-containing proteins are denoted by their ENSEMBL reference (human proteins) or their Wormbase gene name (C. elegans proteins).
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  Crop: Crop_picture: WBPicture0000009763
  Acknowledgment: Template: Reprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>.
    Publication_year: 2004
    Article_URL: DOI id 10.1016/j.cub.2003.12.029
    Journal_URL: CurrentBiology
    Publisher_URL: Elsevier
  Reference: WBPaper00006323