WormBase Tree Display for Picture: WBPicture0000009711
expand all nodes | collapse all nodes | view schema
| WBPicture0000009711 | Description | Figure 2. HMR-1 Acts to Regulate the Morphology of Motor Neurons(A and B) Representative animals expressing GFP under the control of 4 kb of HMR-1B upstream sequences. (A) A lateral view of a first-stage L1 larva. Arrows indicate the cell bodies of the DD class neurons in the VNC, which send out processes during embryonic morphogenesis. The nerve ring is indicated by an arrowhead. (B) A ventral view of an adult (the animal is helically twisted about its head-tail axis due to the activity of the rol-6(su1006) gene used as a transformation marker) showing expression in both ventral (arrowheads) and dorsal (small arrow) nerve cords. Asterisks indicate the position of commissures that extend along the right-hand body wall from the VNC to the DNC. The locations of the nerve ring (NR) and the retrovesicular ganglion (RVG) are indicated.(C) A ventral view of a wild-type adult hermaphrodite showing the right-hand tract of VNC (arrow) visualized by PHMR-1B::gfp expression. Note the position of the cell bodies of the motor neurons, which lie on the ventral midline.(D) A ventral view of a representative HMR-1B mutant showing fasciculation defects in the VNC as visualized by PHMR-1B::gfp expression The arrow indicates an aberrant process running in the left-hand tract.(E) A dorsal view of an HMR-1B mutant, carrying the unc-47::gfp construct, showing inappropriate outgrowth of the VD3 commissure along the left-hand side of the body wall (arrow), coupled with a failure of the VD6 commissure to reach the dorsal nerve cord (+). An asterisk indicates the DD1/VD2 commissure for orientation.The scale bars in (A) and (B) represent 10 um and 100 um, respectively. The scale bar in (C) represents 80 um; (C), (D), and (E) are at the same magnification. Anterior is oriented toward the left in all panels. | |||
|---|---|---|---|---|---|
| Name | F2.jpg | ||||
| Crop | Crop_picture | WBPicture0000009712 | |||
| Acknowledgment | Template | Reprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>. | |||
| Publication_year | 2002 | ||||
| Article_URL | DOI | id | 10.1016/S0960-9822(01)00624-8 | ||
| Journal_URL | CurrentBiology | ||||
| Publisher_URL | Elsevier | ||||
| Reference | WBPaper00005031 |
