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| WBPicture0000009615 | Description | Figure 4. slo-1 Expression in Neurons and Muscle, and Neuron-Specific Effects on Locomotion. (A-D) slo-1 expression and protein localization. (A and C) Whole adult wild-type hermaphrodite worms fixed and stained with anti-BK channel primary antibodies and visualized with FITC-conjugated secondary antibodies. Lateral view showing dense staining in the synapse-rich nerve ring in the head region (A) and punctate immunoreactivity near the surface of body-wall muscle (C). (B and D) Fluorescence images from live wild-type adult hermaphrodite animals expressing the SLO-1a::GFP fusion as an extrachromosomal array. Lateral view showing bright fluorescence in the nerve ring (B) and punctate fluorescence near the surface of body-wall muscle (D).(E) Impact of tissue-specific rescue of slo-1 on locomotion. Locomotion velocities of unc-64, unc-64;slo-1(js118), and two transgenic strains of unc-64;slo-1(js118) transformed with a SLO-1a minigene under the control of either the snb-1 promoter driving expression selectively in neurons or the myo-3 promoter driving expression selectively in body-wall muscle. | |||
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| Name | F4.jpg | ||||
| Crop | Crop_picture | WBPicture0000009616 | |||
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| Acknowledgment | Template | Reprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>. | |||
| Publication_year | 2001 | ||||
| Article_URL | DOI | id | 10.1016/S0896-6273(01)00522-0 | ||
| Journal_URL | Neuron | ||||
| Publisher_URL | Elsevier | ||||
| Reference | WBPaper00005015 |
