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WBPicture0000008429DescriptionFigure 5. AIR-2 kinase is required for localization of condensin proteins during mitosis. (A-D) Wild-type embryo costained with SMC-4 antibody (green, A), DNA dye (red,B), and tubulin antibody (blue, C; merge inD). SMC-4 associates with condensed mitotic chromosomes within mitotic spindles, but not with interphase chromosomes. (Arrowhead) Mitotic nucleus; (arrow) interphase nucleus. (E-H)air-2(RNAi) embryo, stained as above. SMC-4 (E) does not associate with condensed mitotic chromosomes (F) within a tetrapolar mitotic spindle (G; merge in H). (I-L) air-2(RNAi) embryo, costained with HCP-3 antibody (green, I), DNA dye (red, J), and tubulin antibody (blue, K; merge in L). HCP-3 associates with mitotic chromosomes when AIR-2 is depleted.
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CropCrop_pictureWBPicture0000008430
AcknowledgmentTemplateWormBase wishes to thank <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Journal_URL>, <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>.
Publication_year2002
Article_URLDOIid10.1101/gad.968302
Journal_URLGenes&Development
Publisher_URLColdSpringHarborLabPress
ReferenceWBPaper00005173