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WBPicture0000007819DescriptionFigure 1. WTS-1, the putative C. elegans homolog of mammalian Lats kinase, localizes to the subapical region in the intestine. (A) Domain structure of WTS-1 homologs. NTR, N-terminal regulatory domain; HM, hydrophobic motif. Numbers indicate the percentage amino acid identity with respect to wts-1. (B) Ventral view showing wts-1 expression in the vulval precursor cells (VPCs). (a) Fluorescence image; (b) matching Nomarski image, dotted lines indicate VPC outlines. VPC lineages are shown. Arrow indicates WTS-1::GFP expression in the body wall muscle. (C) Embryonic wts-1 expression. Lateral views showing WTS-1::GFP localization in the embryo in the indicated tissues. (D) Time-lapse images of WTS-1::GFP in the intestine during embryogenesis. Ventral enclosure begins at time 0. (E,F) Subcellular localization of WTS-1::GFP in the intestine. wts-1::gfp transgenic embryos were immunostained with PAR-3 (E) and PKC-3 (F) antibodies (red), with WTS-1::GFP in green. Insets in D-F are magnified images. Scale bars: 10 μm.
NameF1.large.jpg
DepictExpr_patternExpr8660
AnatomyWBbt:0005772
WBbt:0005813
WBbt:0007809
Cellular_componentGO:0005737
GO:0005886
AcknowledgmentTemplateWormBase thanks <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>.
Publication_year2009
Article_URLDOIid10.1242/dev.035485
Journal_URLDevelopment
Publisher_URLTheCompanyofBiologists
ReferenceWBPaper00034726