WormBase Tree Display for Picture: WBPicture0000007559

WBPicture0000007559 Description: Figure 6. Laminin alfaA and Laminin alfaB segregate to different basement membranes. Immunofluorescence micrograph of embryos co-stained with Laminin alfa A (red) and Laminin alfaB (green) antibodies. (A) By late gastrulation, both alfa subunits are deposited between the germ layers. While staining for Laminin alfaA is intense around the pharyngeal precursors (p), both subunits are detected between the muscle (m), intestinal (i) and epidermal (e) precursor cells. (B) As the embryo elongates, areas of distinct Laminin alfaA and Laminin alfaB composition can be distinguished between the developing pharynx/intestine (arrowheads) and body wall muscle (arrows). (C) Co-staining of a late stage mnDf90 embryo, in which the pharynx and intestine has detached from the body wall muscle. Laminin alfaA associates with the pharynx and intestine (large arrows) and Laminin alfaB associates with the body wall muscles (arrowheads), suggesting that these basement membranes, which are juxtaposed in wild-type animals, each retain a unique alfa subunit composition. Juxtaposed muscle/epidermis associated membranes appear yellow (small arrows). Anterior is towards the left, dorsal towards the top. Scale bars: 10 um.
  Name: F6.large.jpg
  Depict: Expr_pattern: Expr2621
      Expr2622
    Anatomy: WBbt:0003681
      WBbt:0005772
      WBbt:0005813
    Cellular_component: GO:0005604
  Acknowledgment: Template: WormBase thanks <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>.
    Publication_year: 2003
    Article_URL: DOI id 10.1242/dev.00481
    Journal_URL: Development
    Publisher_URL: TheCompanyofBiologists
  Reference: WBPaper00006014