WormBase Tree Display for Interaction: WBInteraction000558217
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| WBInteraction000558217 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001869 | Interactor_type | Trans_regulator | |
| WBGene00002231 | Interactor_type | Trans_regulated | |||
| Interaction_summary | "KNL-1 still localized to kinetochores in embryos depleted of either ceNDC-80 or HIM-10 (Fig. 5B). However, the level of kinetochore-localized KNL-1 was significantly reduced relative to identically processed control embryos (Fig. 5B)... KNL-1 was reduced to ~50% of wild-type levels in depletions of either CeNDC-80 or HIM-10, suggesting that reduction of KNL-1 protein levels may contribute to the observed reduction of kinetochore-localized KNL-1 in embryos depleted of CeNDC-80 or HIM-10 (Fig. 5B)." | ||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000003 | ||
| Subcellular_localization | kinetochores | ||||
| Paper | WBPaper00006142 | ||||
| Remark | Fig. 5b |
