WormBase Tree Display for Interaction: WBInteraction000558106
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WBInteraction000558106 | Interaction_type | Regulatory | Change_of_localization | ||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene | WBGene00003738 | Interactor_type | Trans_regulator | |
WBGene00006784 | Interactor_type | Trans_regulated | |||
Variation_interactor | WBVar00054142 | Interactor_type | Trans_regulator | ||
Interaction_summary | "We visualized GABAergic postsynaptic NMJ structures using a functional GFP-tagged GABA receptor, UNC-49B (Bamber et al., 1999). We observed defects in the pattern of the UNC-49B::GFP marker that correlated with those seen with the SNB::GFP marker in cle-1 and nid-1 mutants (Fig. 6). In both cle-1 mutants the puncta appear enlarged, rounded, and spaced farther apart than normal. nid-1(cg119) animals exhibited elongated puncta interspersed with smaller smeary puncta. nid-1(cg118) animals have a mix of small puncta and elongated puncta that are spread farther apart." | ||||
Detection_method | Reporter_gene | [UNC-49:GFP] | |||
Regulation_level | Post_translational | ||||
Regulation_result | Positive_regulate | Anatomy_term | WBbt:0005190 | ||
Subcellular_localization | puncta | ||||
Paper | WBPaper00005871 | ||||
Remark | Fig. 6 |