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WormBase Tree Display for Interaction: WBInteraction000558020

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Name Class

WBInteraction000558020Interaction_typeRegulatoryChange_of_localization
InteractorInteractor_overlapping_geneWBGene00004726Interactor_typeTrans_regulator
WBGene00006994Interactor_typeTrans_regulated
WBGene00006988Interactor_typeTrans_regulated
Interaction_summary"We examined the distribution of the PCM components, c-tubulin, ZYG-9, and AIR-1 (Figures 2A-2C and data not shown...Using all three markers, we found that the MTOC in sas-4(RNAi) embryos at the two-cell stage contains a single PCM (Figures 2D-F and data not shown)."
"we examined the distribution of two putative centriolar markers, ZYG-1 and the Polo-like kinase PLK-1. In wild-type, antibodies against both proteins identify a tiny dot in the center of centrosomes, suggesting that ZYG-1 and PLK-1 are present at centrioles or a closely associated structure (Figures 2G-2I and data not shown... Using both markers, we found that the PCM in sas-4(RNAi) embryos at the two-cell stage harbors a single ZYG-1 and PLK-1-containing entity, the size of which does not exceed that observed in wild-type (Figures 2J-2L and data not shown)."
Regulation_levelPost_translational
Regulation_resultPositive_regulateLife_stageWBls:0000007
Subcellular_localizationMTOC
PaperWBPaper00005765
RemarkFig. 2