WormBase Tree Display for Interaction: WBInteraction000557646

WBInteraction000557646 Interaction_type: Regulatory: Change_of_expression_level
  Interactor: Interactor_overlapping_gene: WBGene00003168 Interactor_type: Trans_regulated
    Other_interactor: hypoxia Interactor_type: Trans_regulator
  Interaction_summary: "we used cell-type-specific promoters driving green fluorescent protein (GFP) expression in neurons and muscle (Fig. 2, E to K).... The number of GFP-positive muscle nuclei was significantly reduced, which is consistent with cell death (Fig. 2K). daf-2(e1370) protected myocytes from both nuclear fragmentation and death (Fig. 2, H and K)... Hypoxia also reduced the number of GFP(+) neurons. e1370 mutants did not show neuronal loss and axonal pathology (Fig. 2, J and K)."
  Detection_method: Reporter_gene: [mec-4p::GFP]
  Regulation_level: Transcriptional
  Regulation_result: Negative_regulate: Life_stage: WBls:0000106
      Anatomy_term: WBbt:0005237
  Paper: WBPaper00005310
  Remark: Fig. 2h