WormBase Tree Display for Interaction: WBInteraction000557499
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| WBInteraction000557499 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00000366 | Interactor_type | Trans_regulator | |
| WBGene00001949 | Interactor_type | Trans_regulated | |||
| Interaction_summary | "RNAi inhibition of CBP-1 induces ectopic expression of HLH-2::GFP in non-neuronal cells (Figure 4B, compare panels a and b; Shi and Mello, 1998), a promoter who's activity is restricted to neurons late in C. elegans embryogenesis (Krause et al., 1997). In contrast, inhibition of CBP-1 by RNAi eliminated the expression of HLH-1::GFP and ELT-2::GFP (Figure 4B, compare panels e and h with d and g), promoters that are active in muscle and endodermal cells, respectively (Krause et al., 1990; Fukushige et al., 1998)." | ||||
| Detection_method | Reporter_gene | [hlh-2::GFP] | |||
| Regulation_result | Negative_regulate | Life_stage | WBls:0000003 | ||
| Anatomy_term | WBbt:0005735 | ||||
| Paper | WBPaper00005101 | ||||
| Remark | Fig. 4b |
