WormBase Tree Display for Interaction: WBInteraction000556154
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WBInteraction000556154 | Interaction_type | Regulatory | Change_of_localization | |
---|---|---|---|---|
Interactor | Interactor_overlapping_gene (2) | |||
Interaction_summary | "We found that in the first cell cycle of icp-1(RNAi) embryos, ZEN-4 initially localized to the expected position. However, ZEN-4 did not persist as it does in wild-type embryos; ZEN-4 disappeared after roughly 1-2 minutes (Figure 7; average 1.7 minutes, n = 7). As ZEN-4 and CYK-4 are each required for central spindle assembly, we conclude that, in the first division of icp-1(RNAi) embryos, the central spindle does not stably assemble, thus contributing to the late defects in cytokinesis" | |||
Detection_method | Construct | |||
Reporter_gene | [ZEN-4::GFP] | |||
Transgene | ||||
Regulation_level | Post_translational | |||
Regulation_result | Positive_regulate | Life_stage | WBls:0000003 | |
Subcellular_localization | spindle midzone | |||
Paper | WBPaper00004389 | |||
Remark | Fig. 7 |