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WormBase Tree Display for Interaction: WBInteraction000555717

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Name Class

WBInteraction000555717Interaction_typeRegulatoryChange_of_localization
InteractorInteractor_overlapping_geneWBGene00004897Interactor_typeTrans_regulated
TransgeneWBTransgene00000695
ConstructWBCnstr00000692
WBGene00006751Interactor_typeTrans_regulator
Variation_interactorWBVar00142932Interactor_typeTrans_regulator
Interaction_summary"In wild-type worms, the GFP-tagged synaptobrevin was localized in a punctate pattern in the neuropil of the nervous system similar to the distribution of synaptic varicosities (Nonet, 1999) (Figure 7A). However, in the four unc-11 mutants characterized, the GFP fusion was diffuse and more broadly distributed in the nervous system, resembling the distribution of the plasma membrane protein syntaxin (Saifeeet al., 1998) (Figure 7B)"
Detection_methodConstruct
Reporter_gene[snb-1::gfp]
Transgene
Regulation_levelPost_translational
Regulation_resultPositive_regulateLife_stageWBls:0000041
Anatomy_termWBbt:0003679
Subcellular_localizationvaricosities
PaperWBPaper00003600
RemarkFig. 7ab