WormBase Tree Display for Interaction: WBInteraction000542491
expand all nodes | collapse all nodes | view schema
| WBInteraction000542491 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene (11) | ||||
| Variation_interactor | WBVar00323157 | Interactor_type | Trans_regulator | ||
| WBVar00323165 | Interactor_type | Trans_regulator | |||
| WBVar00090851 | Interactor_type | Trans_regulator | |||
| Interaction_summary | "We focused on miRNA families for which there exist viable deletions of the majority or entirety of the family. We first surveyed these miRNA deletion strains for deregulation of the MRPR genes we identified. Whereas the majority the miRNA deletion strains showed wild-type expression levels of MRPR genes, separate loss of the miR-58 family, lin-4 family, miR-251 family, or miR-253 each resulted in robust and significant upregulation specific subsets of the MRPR genes (Figure 6C)." | ||||
| Detection_method | RT_PCR | ||||
| Paper | WBPaper00040985 | ||||
| Remark | Fig. 6c |
