WormBase Tree Display for Interaction: WBInteraction000542445
expand all nodes | collapse all nodes | view schema
| WBInteraction000542445 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00002393 | Interactor_type | Trans_regulated | |
| WBGene00012261 | Interactor_type | Trans_regulated | |||
| WBGene00012257 | Interactor_type | Trans_regulated | |||
| WBGene00012256 | Interactor_type | Trans_regulated | |||
| WBGene00012255 | Interactor_type | Trans_regulated | |||
| WBGene00020571 | Interactor_type | Trans_regulated | |||
| Molecule_interactor | WBMol:00004852 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "In order to verify the gene regulation, we performed qRT-PCR on the 13 genes from ABU and LPR gene families using four independent MeHg-treated and control samples from L4 animals (Fig. 2). The 6 LPR family members were confirmed to be up regulated and all 7 ABU family members were confirmed to be down-regulated significantly... The lpr genes had more modest fold changes in qRT-PCR than in RNAseq. The most highly up-regulated lpr gene, lpr-4, according to RNA-seq (31-fold) was only 2-fold up-regulated in qRT-PCR." | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000109 | ||
| Paper | WBPaper00043945 | ||||
| Remark | Fig. 2; 10uM MeHg |
