WormBase Tree Display for Interaction: WBInteraction000541241
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| WBInteraction000541241 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene (20) | ||||
| Molecule_interactor | WBMol:00002786 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "Genes which showed the greatest fold up-regulation following IVM exposure in the microarray experiments were further assessed using real- time QPCR. All of the genes examined that were proposed to be up-regulated by the microarray experiments were confirmed to be up-regulated by this technique (Figure 4). sip-1, gst-1 and HSF-1 are genes that have been associated general stress responses. These were included in the RT-QPCR analysis as negative controls and none showed any evidence of induction, supporting the earlier conclusion of a lack of a generalised stress response to IVM exposure." | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Paper | WBPaper00040808 | ||||
| Remark | Fig. 4; 1 ug/mL [1.1uM] Ivermectin (Virbamec) |
