WormBase Tree Display for Interaction: WBInteraction000537294
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| WBInteraction000537294 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001069 | Interactor_type | Trans_regulated | |
| Antibody | WBAntibody00001857 | ||||
| WBGene00001067 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00142941 | Interactor_type | Trans_regulator | ||
| Interaction_summary | "This ability of a mutation in one collagen to affect others was further confirmed for the non-stage-specific collagen DPY-7, after costaining of the TP14:dpy-5(e61)I;kaIs12(col-19::gfp) strain with the DPY-7 monoclonal antibodies (Fig. 3C, red). In the dorsal/ventral hypodermal cells, DPY-7 localized in a regular but constricted pattern that corresponded to the annular furrows (Fig. 3C, denoted an) and was similar to the COL-19::GFP patterns observed in wild-type and in dpy-5 mutants. Conversely, in the matrix overlying the lateral seam cell cords, DPY-7 expression was abnormal: the DPY-7 staining pattern appeared broken (Fig. 3C, denoted by double-headed arrow) and generally deviated from the wildtype staining pattern in which both annuli (COL-19) and annular furrows (DPY-7) normally extend to appose the lateral ala (Fig. 1C)." | ||||
| Detection_method | Antibody | ||||
| Paper | WBPaper00005747 | ||||
| Remark | Figure 3 |
