WormBase Tree Display for Interaction: WBInteraction000536825
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WBInteraction000536825 | Interaction_type | Regulatory | Change_of_expression_level | ||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene (17) | ||||
Variation_interactor | WBVar00088492 | Interactor_type | Trans_regulator | ||
Interaction_summary | "While ATP synthase subunit alpha H28016.1 (Q9XXK1) did not show any significant regulation in the proteomics data set or the western blot analysis, heat shock protein HSP-60 (P50140) was significantly downregulated in pept-1, as was also observed in western blot analysis. Furthermore, the low expression of two proteins involved in C1 metabolism, S-adenosyl methionine synthetase SAMS-1 (O17680) and S-adenosyl homocysteine hydrolase AHCY-1 (P27604), confirmed earlier data from our group... 75% of these 20 proteins (Figure 2A; Table S2) revealed decreased levels in pept-1 as compared to levels in wild-type animals, whereas only 5 proteins displayed increased levels." | ||||
Paper | WBPaper00045460 | ||||
Remark | Figure 2A; Table S2 |