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WormBase Tree Display for Interaction: WBInteraction000524579

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Name Class

WBInteraction000524579Interaction_typeRegulatoryChange_of_localization
InteractorInteractor_overlapping_geneWBGene00002299Interactor_typeTrans_regulated
Expr_patternExpr688
TransgeneWBTransgene00000520
ConstructWBCnstr00012492
WBGene00002991Interactor_typeTrans_regulator
Variation_interactorWBVar00143908Interactor_typeTrans_regulator
Interaction_summaryLET- 23::GFP was mislocalized in a significant fraction of animals in both the lin-7 and lin-2 strains at both times of development (1-3 hr or 3-4.5 hr after the L2 molt). LET-23::GFP appears dispersed throughout the apical membrane domain rather than localized to a ring at the cell junctions. Different focal planes of these examples show that LET-23::GFP is predominantly located in the apical membrane domain, with little LET-23::GFP appearing in the basal membrane domain.
Detection_methodConstruct
Transgene
Regulation_resultPositive_regulateAnatomy_termWBbt:0008117
WBbt:0008121
WBbt:0008125
WBbt:0008129
WBbt:0008133
PaperWBPaper00002436