WormBase Tree Display for Interaction: WBInteraction000523962
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| WBInteraction000523962 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003007 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr3049 | ||||
| Transgene | WBTransgene00020257 | ||||
| WBGene00003241 | Interactor_type | Trans_regulator | |||
| Interaction_summary | RNAi against cam-1/Ror, mom-2/Wnt, egl- 20/Wnt, apr-1/APC, dsh-2/dishevelled and mig-5/dishevelled resulted in a decrease in the nuclear level of LIN-18ICD expressed under the control of the lin-18 promoter. Quantitative measurements of the nuclear localization revealed that RNAi against cam-1, mom-2, dsh-2 and mig-5 significantly reduced the nuclear localization of LIN-18ICD. | ||||
| Detection_method | Reporter_gene | [lin-18::GFP} | |||
| Transgene | |||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Subcellular_localization | nucleus | ||
| Interaction_RNAi | WBRNAi00101956 | ||||
| Paper | WBPaper00045442 |
