WormBase Tree Display for Interaction: WBInteraction000505167
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| WBInteraction000505167 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00002016 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr2757 | ||||
| Transgene | WBTransgene00000416 | ||||
| Construct | WBCnstr00000416 | ||||
| WBGene00001328 | Interactor_type | Trans_regulator | |||
| Interaction_summary | Reducing the expression of epi-1 by RNAi did not cause any detectable nuclear accumulation of DAF-16::GFP nor induction of hsp-16.2 (not shown). When challenged with heat stress, epi-1 RNAi did not affect the ability to relocate DAF-16 to the nucleus, but hsp-16.2::GFP expression in epi-1(RNAi) worms was significantly lower than EV (empty vector). This shows that epi-1 depletion interferes with heat stress induction of hsp-16.2. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [hsp-16.2::gfp] | ||||
| Transgene | |||||
| Regulation_level | Transcriptional | ||||
| Paper | WBPaper00040382 |
