WormBase Tree Display for Interaction: WBInteraction000504725
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| WBInteraction000504725 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001130 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00008011 | ||||
| Construct | WBCnstr00007760 | ||||
| WBGene00006791 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00143185 | Interactor_type | Trans_regulator | ||
| Interaction_summary | GFP-tagged dynamin (DYN- 1::GFP) and the AP2a-subunit (APT-4::GFP) were both localized to diffraction-limited puncta adjacent to presynaptic elements (labeled with mRFP::SNB-1), suggesting that these reporters are localized to perisynaptic endocytic zones. DYN-1 and APT-4 puncta intensities were significantly increased in unc-57 mutants, indicating increased synaptic abundance when endophilin was absent. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [dyn-1::gfp] | ||||
| Transgene | |||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Negative_regulate | Subcellular_localization | diffraction-limited puncta adjacent to presynaptic elements | ||
| Paper | WBPaper00037929 |
