WormBase Tree Display for Interaction: WBInteraction000503525
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| WBInteraction000503525 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003916 | Interactor_type | Trans_regulator | |
| WBGene00000386 | Interactor_type | Trans_regulated | |||
| Variation_interactor | WBVar00000381 | Interactor_type | Trans_regulator | ||
| Interaction_summary | CDC-25.1 is enriched in the anterior cytoplasm of the one-cell embryo. PLK-1 distribution is uniform at meiosis and then becomes asymmetric by pronuclear migration. From metaphase of P0 to the end of the two-cell stage, all embryos continue to show anterior enrichment of CDC-25.1. The asymmetries of PLK-1 is lost in par-1 mutants, with AB and P1 cells showing equivalent distributions. | ||||
| Detection_method | Reporter_gene | [cdc-25.1::gfp], translaitonal fusion. | |||
| Regulation_level | Transcriptional | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000007 | ||
| Anatomy_term | WBbt:0004015 | ||||
| Subcellular_localization | anterior cytoplasm | ||||
| Paper | WBPaper00031567 |
