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WormBase Tree Display for Gene: WBGene00044319

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Name Class

WBGene00044319SMapS_parentSequenceW06E11
IdentityVersion2
NameCGC_nametag-266
Sequence_nameW06E11.5
Molecular_nameW06E11.5a
W06E11.5a.1
CE26024
W06E11.5b
CE01430
W06E11.5b.1
Other_namechicAccession_evidenceEMBLAF248541
CELE_W06E11.5Accession_evidenceNDBBX284603
Public_nametag-266
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change122 Apr 2005 11:55:18WBPerson2970EventCreated
216 Jun 2006 12:16:17WBPerson2970EventAcquires_mergeWBGene00021064
Acquires_mergeWBGene00021064
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtag
Allele (46)
StrainWBStrain00032589
WBStrain00036116
RNASeq_FPKM (74)
GO_annotation00077616
Contained_in_operonCEOP3028
Ortholog (38)
Structured_descriptionConcise_descriptionW06E11.5/tag-266 encodes a cysteine-rich hydrophobic (CHIC) protein orthologous to human CHIC1/BRX and CHIC2/BTL; by orthology to human CHIC2, cysteine residues in the C-terminal CHIC domain of W06E11.5B are predicted to be palmitoylated, and this hydrophobic domain is expected to bind W06E11.5B to Golgi vesicles and the plasma membrane; however, W06E11.5 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00032045
WBPaper00032046
WBPaper00032047
Curator_confirmedWBPerson567
Date_last_updated24 Jul 2008 00:00:00
Automated_descriptionPredicted to be located in membrane. Used to study cancer. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Is an ortholog of human CHIC2 (cysteine rich hydrophobic domain 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:162Homo sapiensPaper_evidenceWBPaper00027758
Curator_confirmedWBPerson324
Date_last_updated13 Mar 2023 00:00:00
Potential_modelDOID:9119Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1935)
Models_disease_in_annotationWBDOannot00000204
Molecular_infoCorresponding_CDSW06E11.5a
W06E11.5b
Corresponding_transcriptW06E11.5a.1
W06E11.5b.1
Other_sequence (12)
Associated_featureWBsf650809
WBsf655415
Experimental_infoRNAi_result (14)
Expr_patternExpr1014583
Expr1040223
Expr1158437
Expr2017253
Expr2035389
Drives_constructWBCnstr00023631
Construct_productWBCnstr00023631
Microarray_results (28)
Expression_cluster (75)
Interaction (13)
Map_infoMapIIIPosition-26.4018Error0.011813
PositivePositive_cloneW06E11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene