WormBase Tree Display for Gene: WBGene00022874

WBGene00022874 SMap: S_parent: Sequence: ZK1248
  Identity: Version: 2
    Name: CGC_name: nep-25 Person_evidence: WBPerson260
      Sequence_name: ZK1248.1
      Molecular_name: ZK1248.1
        ZK1248.1.1
        CE35373
      Other_name: CELE_ZK1248.1 Accession_evidence: NDB BX284602
      Public_name: nep-25
    DB_info: Database: AceView gene 2G133
        WormQTL gene WBGene00022874
        WormFlux gene WBGene00022874
        NDB locus_tag CELE_ZK1248.1
        Panther gene CAEEL|WormBase=WBGene00022874|UniProtKB=Q23427
          family PTHR11733
        NCBI gene 191543
        RefSeq protein NM_062763.3
        TREEFAM TREEFAM_ID TF319427
        TrEMBL UniProtAcc Q23427
        UniProt_GCRP UniProtAcc Q23427
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:06 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 10 Feb 2012 15:49:10 WBPerson2970 Name_change: CGC_name: nep-25
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nep
    Allele (39)
    Strain: WBStrain00037465
    RNASeq_FPKM (74)
    GO_annotation: 00078422
      00078423
      00078424
      00126840
      00126841
      00126842
    Ortholog (31)
    Paralog (24)
    Structured_description: Concise_description: ZK1248.1 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; ZK1248.1 has no clear orthologs in other organisms. Paper_evidence: WBPaper00004584
            WBPaper00013276
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: ZK1248.1
    Corresponding_CDS_history: ZK1248.1:wp106
    Corresponding_transcript: ZK1248.1.1
    Other_sequence: CJC05800_1
      CBC12704_1
    Associated_feature: WBsf987969
      WBsf1012268
      WBsf221350
  Experimental_info: RNAi_result: WBRNAi00022512 Inferred_automatically: RNAi_primary
      WBRNAi00059180 Inferred_automatically: RNAi_primary
      WBRNAi00089214 Inferred_automatically: RNAi_primary
      WBRNAi00038181 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1023275
      Expr1162599
      Expr2013970
      Expr2032209
    Drives_construct: WBCnstr00023902
    Construct_product: WBCnstr00023902
    Microarray_results (18)
    Expression_cluster (72)
    Interaction: WBInteraction000380431
      WBInteraction000383543
      WBInteraction000410853
  Map_info: Map: II Position: -0.866729
    Positive: Positive_clone: ZK1248 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene