WormBase Tree Display for Gene: WBGene00022793

WBGene00022793 SMap: S_parent: Sequence: ZK686
  Identity: Version: 1
    Name: Sequence_name: ZK686.3
      Molecular_name: ZK686.3
        ZK686.3.1
        CE00457
      Other_name: CELE_ZK686.3 Accession_evidence: NDB BX284603
      Public_name: ZK686.3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:06 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (24)
    RNASeq_FPKM (74)
    GO_annotation: 00043879
      00043880
      00043881
      00043882
      00043883
    Contained_in_operon: CEOP3452
    Ortholog: WBGene00064084 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00023541 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00161530 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00119842 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00091280 Pristionchus pacificus From_analysis: OMA
            WormBase-Compara
      WBGene00227795 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g4216 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g6607 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g12233 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g5318 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g3157 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g6545 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g9121 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g720 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g7832 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g3117 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00378.g9994 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cang_2012_03_13_00378.g9995 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-ZK686.3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold630.g17230 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_02310.g25918 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_08014 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_009123 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g04001 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g13257 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30041800 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g8220 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00244768 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00260792 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00297261 Trichuris muris From_analysis: WormBase-Compara
      WBGene00297658 Trichuris muris From_analysis: WormBase-Compara
      WBGene00298867 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000005611 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      SGD:S000004481 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            OrthoFinder
            Panther
            PhylomeDB
      FB:FBgn0032015 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-3667 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050522-381 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:30242 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:28880 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1914325 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1933134 Mus musculus From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:620094 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1303318 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: ZK686.3 is orthologous to the putative tumor suppressor candidate 3 (TUSC3); TUSC3 is involved in plasma membrane magnesium ion transport; ZK686.3 is also orthologous to the S. cerevisiae dolichyl-diphosphooligosaccharide-protein glycotransferase gamma chain (34-kD) subunit, OST3. Paper_evidence: WBPaper00013569
            WBPaper00013570
          Curator_confirmed: WBPerson324
            WBPerson1823
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be involved in protein N-linked glycosylation via asparagine. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Used to study bacterial infectious disease. Human ortholog(s) of this gene implicated in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia; autosomal recessive intellectual developmental disorder 7; and congenital disorder of glycosylation Icc. Is an ortholog of human MAGT1 (magnesium transporter 1) and TUSC3 (tumor suppressor candidate 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:104 Homo sapiens Paper_evidence: WBPaper00059373
          Curator_confirmed: WBPerson324
          Date_last_updated: 09 Mar 2023 00:00:00
    Potential_model: DOID:0081183 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:30242)
      DOID:0080319 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:28880)
      DOID:0111839 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:28880)
  Models_disease_in_annotation: WBDOannot00000065
  Molecular_info: Corresponding_CDS: ZK686.3
    Corresponding_transcript: ZK686.3.1
    Other_sequence (72)
    Associated_feature: WBsf667103
      WBsf667104
      WBsf667105
      WBsf227023
  Experimental_info: RNAi_result (26)
    Expr_pattern: Expr1010721
      Expr1040083
      Expr1163077
      Expr2008936
      Expr2027172
    Drives_construct: WBCnstr00023970
    Construct_product: WBCnstr00023970
    Microarray_results (21)
    Expression_cluster (111)
    Interaction (99)
  Map_info: Positive: Positive_clone: ZK686 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III -0.603948
  Reference: WBPaper00029024
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
  Method: Gene