WormBase Tree Display for Gene: WBGene00022599

WBGene00022599 SMap: S_parent: Sequence: ZC395
  Identity: Version: 2
    Name: CGC_name: daf-41 Paper_evidence: WBPaper00046600
          Person_evidence: WBPerson759
      Sequence_name: ZC395.10
      Molecular_name: ZC395.10
        ZC395.10.1
        CE01436
      Other_name: CELE_ZC395.10 Accession_evidence: NDB BX284603
      Public_name: daf-41
    DB_info: Database: AceView gene 3G364
        WormQTL gene WBGene00022599
        WormFlux gene WBGene00022599
        NDB locus_tag CELE_ZC395.10
        Panther gene CAEEL|WormBase=WBGene00022599|UniProtKB=Q23280
          family PTHR22932
        NCBI gene 175727
        RefSeq protein NM_065725.5
        SwissProt UniProtAcc Q23280
        TREEFAM TREEFAM_ID TF315077
        UniProt_GCRP UniProtAcc Q23280
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:06 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 21 Sep 2017 11:27:19 WBPerson2970 Name_change: CGC_name: daf-41
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: daf
    Allele (15)
    Strain: WBStrain00001518
      WBStrain00032911
      WBStrain00032936
      WBStrain00037205
    RNASeq_FPKM (74)
    GO_annotation: 00077908
      00077909
      00077910
      00077911
      00077912
      00077913
      00077914
      00126638
    Contained_in_operon: CEOP3276
    Ortholog (42)
    Structured_description: Automated_description: Predicted to enable Hsp90 protein binding activity and protein-folding chaperone binding activity. Predicted to be involved in chaperone-mediated protein complex assembly and protein folding. Located in myofibril. Expressed in several structures, including amphid neurons; anal depressor muscle; phasmid neurons; touch receptor neurons; and vulva. Human ortholog(s) of this gene implicated in atherosclerosis; breast cancer; and oligodendroglioma. Is an ortholog of human PTGES3 (prostaglandin E synthase 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3181 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:16049)
      DOID:1936 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:16049)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:16049)
  Molecular_info: Corresponding_CDS: ZC395.10
    Corresponding_transcript: ZC395.10.1
    Other_sequence (49)
    Associated_feature: WBsf651041
      WBsf655434
      WBsf226659
  Experimental_info: RNAi_result (12)
    Expr_pattern (12)
    Drives_construct: WBCnstr00002375
      WBCnstr00004326
      WBCnstr00024122
    Construct_product: WBCnstr00013931
      WBCnstr00024122
      WBCnstr00040348
    Microarray_results (20)
    Expression_cluster (160)
    Interaction (160)
  Map_info: Map: III Position: -1.84928
    Positive: Positive_clone: ZC395 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (16)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene