WormBase Tree Display for Gene: WBGene00022459
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| WBGene00022459 | SMap | S_parent | Sequence | Y110A7A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | Sequence_name | Y110A7A.9 | |||||||
| Molecular_name | Y110A7A.9a | ||||||||
| Y110A7A.9a.1 | |||||||||
| CE28105 | |||||||||
| Y110A7A.9b | |||||||||
| CE37057 | |||||||||
| Y110A7A.9b.1 | |||||||||
| Y110A7A.9b.2 | |||||||||
| Y110A7A.9b.3 | |||||||||
| Other_name | CELE_Y110A7A.9 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | Y110A7A.9 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:05 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Allele (54) | |||||||||
| Strain | WBStrain00003412 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00022044 | ||||||||
| Ortholog (39) | |||||||||
| Structured_description | Concise_description | Y110A7A.9 is orthologous to the human WD Repeat-Containing Protein 11(WDR11) which has 6 putative WD40 repeats, a predicted transmembrane region and a tyrosine kinase phosphorylation site; WDR11 is believed to be a tumor suppressor gene. | Paper_evidence | WBPaper00038491 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 25 Jul 2012 00:00:00 | ||||||||
| Automated_description | Predicted to be located in cytoplasm. Expressed in head. Used to study high grade glioma. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder and hypogonadotropic hypogonadism 14 with or without anosmia. Is an ortholog of human WDR11 (WD repeat domain 11). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:3070 | Homo sapiens | Paper_evidence | WBPaper00038491 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 01 May 2023 00:00:00 | ||||||||
| Potential_model | DOID:0090087 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13831) | |||||
| DOID:0060308 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13831) | ||||||
| Disease_relevance | Y110A7A.9 is orthologous to the human WD Repeat-Containing Protein 11(WDR11), which is believed to be a tumor suppressor gene, alterations of which are involved in tumorigenesis of glial and other tumors. | Homo sapiens | Accession_evidence | OMIM | 606417 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 25 Jul 2012 00:00:00 | ||||||||
| Models_disease_in_annotation | WBDOannot00000093 | ||||||||
| Molecular_info | Corresponding_CDS | Y110A7A.9a | |||||||
| Y110A7A.9b | |||||||||
| Corresponding_CDS_history | Y110A7A.9:wp126 | ||||||||
| Corresponding_transcript | Y110A7A.9a.1 | ||||||||
| Y110A7A.9b.1 | |||||||||
| Y110A7A.9b.2 | |||||||||
| Y110A7A.9b.3 | |||||||||
| Other_sequence (35) | |||||||||
| Associated_feature | WBsf643268 | ||||||||
| WBsf643269 | |||||||||
| WBsf656285 | |||||||||
| WBsf976688 | |||||||||
| WBsf976689 | |||||||||
| WBsf976690 | |||||||||
| WBsf976691 | |||||||||
| WBsf976692 | |||||||||
| WBsf1009769 | |||||||||
| WBsf217624 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00117128 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00078501 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00036560 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078502 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002406 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00004526 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00055330 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram371 | ||||||||
| Expr6883 | |||||||||
| Expr1018563 | |||||||||
| Expr1039923 | |||||||||
| Expr1158870 | |||||||||
| Expr2007016 | |||||||||
| Expr2025242 | |||||||||
| Drives_construct | WBCnstr00003879 | ||||||||
| WBCnstr00024225 | |||||||||
| Construct_product | WBCnstr00024225 | ||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (65) | |||||||||
| Map_info | Positive | Positive_clone | Y110A7A | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | I | -0.399393 | |||||||
| Reference | WBPaper00033118 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064339 | |||||||||
| Method | Gene |
