WormBase Tree Display for Gene: WBGene00022356
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WBGene00022356 | SMap | S_parent | Sequence | Y92C3A | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | eak-3 | |||||||
Sequence_name | Y92C3A.3 | ||||||||
Molecular_name | Y92C3A.3 | ||||||||
Y92C3A.3.1 | |||||||||
CE26310 | |||||||||
Other_name | CELE_Y92C3A.3 | Accession_evidence | NDB | BX284603 | |||||
Public_name | eak-3 | ||||||||
DB_info | Database | AceView | gene | 3C258 | |||||
WormQTL | gene | WBGene00022356 | |||||||
WormFlux | gene | WBGene00022356 | |||||||
NDB | locus_tag | CELE_Y92C3A.3 | |||||||
NCBI | gene | 190782 | |||||||
RefSeq | protein | NM_064942.2 | |||||||
TREEFAM | TREEFAM_ID | TF318022 | |||||||
TrEMBL | UniProtAcc | Q9BL23 | |||||||
UniProt_GCRP | UniProtAcc | Q9BL23 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:05 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 25 Jan 2008 14:24:07 | WBPerson2970 | Name_change | CGC_name | eak-3 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | eak | ||||||||
Allele (50) | |||||||||
Strain | WBStrain00003888 | ||||||||
RNASeq_FPKM (74) | |||||||||
Ortholog | WBGene00160227 | Caenorhabditis brenneri | From_analysis | TreeFam | |||||
WBGene00137217 | Caenorhabditis japonica | From_analysis | TreeFam | ||||||
Sp34_40025900 | Caenorhabditis inopinata | From_analysis | WormBase-Compara | ||||||
chrIII_pilon.g6893 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Paralog | WBGene00007226 | ||||||||
Structured_description | Concise_description | eak-3 encodes a protein required for the subset of DAF-16 functions controlling dauer development, but not for lifespan regulation; EAK-3 is expressed in XXX cells, and localizes to the plasma membrane, probably by N-terminal myristoylation; EAK-3 acts in a genetic pathway parallel to that of AKT-1, which may include AKT-2, EAK-4, EAK-6, or SDF-9; EAK-3 has no homologs outside of C. elegans itself, has 20% leucine-like residues, and has a single predicted coiled-coil domain; eak-3 mutants have a very weak dauer arrest phenotype at 25 deg. C., but strongly enhance the dauer arrest phenotype of akt-1(mg306), and enhances expression of the DAF-16 target sod-3; eak-3's dauer arrest and sod-3 overexpression phenotypes require DAF-12 and DAF-16; however, EAK-3 has no effect on lifespan. | Paper_evidence | WBPaper00027748 | |||||
WBPaper00031480 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 15 Feb 2008 00:00:00 | ||||||||
Automated_description | Expressed in XXXL and XXXR. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | Y92C3A.3 | |||||||
Corresponding_transcript | Y92C3A.3.1 | ||||||||
Associated_feature | WBsf650836 | ||||||||
WBsf226184 | |||||||||
Experimental_info | RNAi_result | WBRNAi00058622 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr7894 | ||||||||
Expr1022833 | |||||||||
Expr1039862 | |||||||||
Expr1162042 | |||||||||
Expr2011146 | |||||||||
Expr2029382 | |||||||||
Drives_construct | WBCnstr00012973 | ||||||||
Microarray_results (12) | |||||||||
Expression_cluster (26) | |||||||||
Interaction | WBInteraction000009220 | ||||||||
WBInteraction000052260 | |||||||||
WBInteraction000052261 | |||||||||
WBInteraction000052273 | |||||||||
WBInteraction000052311 | |||||||||
WBInteraction000052337 | |||||||||
WBInteraction000052817 | |||||||||
WBInteraction000052818 | |||||||||
WBInteraction000503471 | |||||||||
WBInteraction000503472 | |||||||||
Map_info | Map | III | Position | -22.6435 | Error | 0.008444 | |||
Positive | Positive_clone | Y92C3A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00027748 | ||||||||
WBPaper00031480 | |||||||||
WBPaper00036004 | |||||||||
WBPaper00036472 | |||||||||
WBPaper00038936 | |||||||||
WBPaper00060179 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |