WormBase Tree Display for Gene: WBGene00021710

WBGene00021710 SMap: S_parent: Sequence: Y49C4A
  Identity: Version: 2
    Name: CGC_name: cyp-33C11
      Sequence_name: Y49C4A.9
      Molecular_name: Y49C4A.9
        Y49C4A.9.1
        CE22218
      Other_name: Y49C4A.a Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_Y49C4A.9 Accession_evidence: NDB BX284605
      Public_name: cyp-33C11
    DB_info: Database: AceView gene 5B190
        WormQTL gene WBGene00021710
        WormFlux gene WBGene00021710
        NDB locus_tag CELE_Y49C4A.9
        Panther gene CAEEL|WormBase=WBGene00021710|UniProtKB=Q965T7
          family PTHR24300
        NCBI gene 190065
        RefSeq protein NM_070902.2
        TrEMBL UniProtAcc Q965T7
        UniProt_GCRP UniProtAcc Q965T7
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 21 Sep 2004 09:38:16 WBPerson1971 Name_change: CGC_name: cyp-33C11
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cyp
    Allele (189)
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (123)
    Paralog (44)
    Structured_description: Automated_description: Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Is an ortholog of human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:783 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2622)
      DOID:1073 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2622)
  Molecular_info: Corresponding_CDS: Y49C4A.9
    Corresponding_transcript: Y49C4A.9.1
    Other_sequence: GR13017
      BXC01796_1
      GRC02118_1
    Associated_feature: WBsf1019093
  Experimental_info: RNAi_result: WBRNAi00095081 Inferred_automatically: RNAi_primary
      WBRNAi00057001 Inferred_automatically: RNAi_primary
      WBRNAi00037285 Inferred_automatically: RNAi_primary
      WBRNAi00092664 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1014100
      Expr1160448
      Expr2010711
      Expr2028950
    Drives_construct: WBCnstr00024450
    Construct_product: WBCnstr00024450
    Microarray_results (16)
    Expression_cluster (39)
    Interaction (34)
  Map_info: Map: V Position: -19.9605
    Positive: Positive_clone: Y49C4A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00042257
    WBPaper00055090
    WBPaper00065080
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene