WormBase Tree Display for Gene: WBGene00021515

WBGene00021515 SMap: S_parent: Sequence: Y41D4B
  Identity: Version: 2
    Name: CGC_name: set-23 Person_evidence: WBPerson1730
            WBPerson268
            WBPerson632
      Sequence_name: Y41D4B.12
      Molecular_name: Y41D4B.12a
        Y41D4B.12a.1
        CE27623
        Y41D4B.12b
        CE31647
        Y41D4B.12a.2
        Y41D4B.12b.1
      Other_name: CELE_Y41D4B.12 Accession_evidence: NDB BX284604
      Public_name: set-23
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 03 May 2007 10:33:07 WBPerson2970 Name_change: CGC_name: set-23
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: set
    Allele (126)
    RNASeq_FPKM (74)
    GO_annotation (17)
    Contained_in_operon: CEOP4047
    Ortholog (45)
    Paralog (19)
    Structured_description: Concise_description: set-23 encodes, by alternative splicing, one isoform of a putative histone H3 lysine-9 methyltransferase orthologous to human SETMAR (OMIM:609834); set-23(n4496) has an embryonic lethal phenotype. Paper_evidence: WBPaper00030864
            WBPaper00031077
            WBPaper00031078
            WBPaper00031079
          Curator_confirmed: WBPerson567
          Date_last_updated: 11 Oct 2007 00:00:00
      Automated_description: Predicted to enable double-stranded DNA binding activity and histone methyltransferase activity. Predicted to be involved in chromatin remodeling and methylation. Predicted to be located in chromosome and nucleus. Expressed in hypodermis. Is an ortholog of human SETMAR (SET domain and mariner transposase fusion gene). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y41D4B.12a
      Y41D4B.12b
    Corresponding_transcript: Y41D4B.12a.1
      Y41D4B.12a.2
      Y41D4B.12b.1
    Other_sequence: CBC00896_1
      AE03310
      CR10636
      CRC09922_1
      Acan_isotig13862
      JG463663.1
      AYC01663_1
    Associated_feature: WBsf227959
  Experimental_info: RNAi_result: WBRNAi00109170 Inferred_automatically: RNAi_primary
      WBRNAi00109462 Inferred_automatically: RNAi_primary
      WBRNAi00020475 Inferred_automatically: RNAi_primary
      WBRNAi00109365 Inferred_automatically: RNAi_primary
      WBRNAi00020480 Inferred_automatically: RNAi_primary
      WBRNAi00109559 Inferred_automatically: RNAi_primary
      WBRNAi00056379 Inferred_automatically: RNAi_primary
      WBRNAi00113456 Inferred_automatically: RNAi_primary
      WBRNAi00109268 Inferred_automatically: RNAi_primary
      WBRNAi00091507 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr14364
      Expr1028038
      Expr1039405
      Expr1159866
      Expr2015768
      Expr2034001
    Microarray_results (25)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00040285:H2S_24hr_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045974:NSM_enriched_DSN-treated_RNAseq
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_downregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050859:downregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:body-muscle_enriched
      WBPaper00050990:body-muscle_expressed
      WBPaper00051039:germline_enriched
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056293:rpl-5(0)-rpl-33(0)_upregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057161:meg-3(tm4259)_meg-4(ax2026)_upregulated_endo-siRNA_targets
      WBPaper00057162:meg-3_meg-4_upregulated_sRNA
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00060661:hypoxia_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061340:Parent_of_hyp1V_and_ant_arc_V
      WBPaper00061340:Parent_of_K_Kprime
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061527:F54E7.8-orc-5_6376
      WBPaper00062146:MOG-7-degron_2h_regulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064716:paraquat_upregulated
      WBPaper00065158:AFD_enriched
      WBPaper00065945:global-rpoa-2(-)_upregulated_transcript
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00036375:depleted_in_PVD_OLL
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(83_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(41_min)
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:Cluster_F
    Interaction (46)
  Map_info: Map: IV Position: -16.5598 Error: 0.016315
    Positive: Positive_clone: Y41D4B Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00030864
    WBPaper00032309
    WBPaper00038372
    WBPaper00038491
    WBPaper00055090
    WBPaper00057162
    WBPaper00065308
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene