WormBase Tree Display for Gene: WBGene00021463
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| WBGene00021463 | SMap | S_parent | Sequence | Y39G10AR | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | zeel-1 | Person_evidence | WBPerson5224 | |||||
| WBPerson7191 | |||||||||
| WBPerson7165 | |||||||||
| Sequence_name | Y39G10AR.5 | ||||||||
| Molecular_name | Y39G10AR.5 | ||||||||
| Y39G10AR.5.1 | |||||||||
| CE36737 | |||||||||
| Other_name | CELE_Y39G10AR.5 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | zeel-1 | ||||||||
| DB_info | Database | AceView | gene | 1C917 | |||||
| WormQTL | gene | WBGene00021463 | |||||||
| WormFlux | gene | WBGene00021463 | |||||||
| NDB | locus_tag | CELE_Y39G10AR.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00021463|UniProtKB=Q95XQ4 | |||||||
| family | PTHR12904 | ||||||||
| NCBI | gene | 189770 | |||||||
| RefSeq | protein | NM_058565.4 | |||||||
| TREEFAM | TREEFAM_ID | TF322626 | |||||||
| TrEMBL | UniProtAcc | Q95XQ4 | |||||||
| UniProt_GCRP | UniProtAcc | Q95XQ4 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:04 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 14 Jan 2008 11:13:19 | WBPerson2970 | Name_change | CGC_name | zeel-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | zeel | ||||||||
| Allele (114) | |||||||||
| Possibly_affected_by | WBVar02158632 | ||||||||
| Strain | WBStrain00037300 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00089220 | ||||||||
| 00089221 | |||||||||
| Ortholog (15) | |||||||||
| Paralog (32) | |||||||||
| Structured_description | Concise_description | zeel-1 encodes a large (917-residue) putative membrane protein, probably enriched in male soma, that is required for compatibility between the Bristol N2 and Hawaiian CB4856 strains of C. elegans; ZEEL-1 has a ~200-residue N-terminal region with six predicted transmembrane sequences, followed by a ~700-residue C-terminal region with normal (globular) amino acid composition but with no known protein motifs; the globular domain of ZEEL-1 has at least 18 C. elegans paralogs, and is divergently related to ZYG-11 and its metazoan orthologs; ZEEL-1 is required zygotically for the viability of embryos also carrying a paternal peel-1(CB4856) allele; a naturally occurring zeel-1 deletion in CB4856, a Hawaiian C. elegans strain, is zygotically lethal with paternal peel-1(Hawaii), and thus is genetically incompatible with C. elegans N2 Bristol; zeel-1 alleles from N2 and CB4856 are embedded in haplotypes that are both present in C. elegans wild populations, and are likely to comprise a balanced polymorphism under some (unknown) form of continuing positive selection; zeel-1 transcripts are enriched in male somatic tissues; other than lethality with paternal peel-1(Hawaii), zeel-1 deletion mutants have no known phenotype, and ZEEL-1 has no obvious function in mass RNAi assays. | Paper_evidence | WBPaper00006390 | |||||
| WBPaper00031387 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 14 Jan 2008 00:00:00 | ||||||||
| Automated_description | Predicted to be located in membrane. Predicted to be part of Cul2-RING ubiquitin ligase complex. Expressed in embryonic cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y39G10AR.5 | |||||||
| Corresponding_CDS_history | Y39G10AR.5:wp124 | ||||||||
| Corresponding_transcript | Y39G10AR.5.1 | ||||||||
| Associated_feature | WBsf643092 | ||||||||
| WBsf982856 | |||||||||
| WBsf1009325 | |||||||||
| WBsf217299 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00004587 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00056278 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9636 | ||||||||
| Expr9637 | |||||||||
| Expr1020197 | |||||||||
| Expr1039377 | |||||||||
| Expr1159761 | |||||||||
| Expr2018124 | |||||||||
| Expr2036261 | |||||||||
| Drives_construct | WBCnstr00008919 | ||||||||
| WBCnstr00009953 | |||||||||
| WBCnstr00009954 | |||||||||
| WBCnstr00009956 | |||||||||
| WBCnstr00009957 | |||||||||
| WBCnstr00009958 | |||||||||
| WBCnstr00024546 | |||||||||
| Construct_product (11) | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (160) | |||||||||
| Interaction | WBInteraction000586296 | ||||||||
| Map_info | Map | I | Position | -9.11843 | Error | 0.025587 | |||
| Positive | Positive_clone | Y39G10AR | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
