[Hanna-Rose W] cog for connection of gonad defective, anchor cell fails to clear opening between uterus and vulva, egg laying defective, about 75 percent of hermaphrodites bag
pnc-1 encodes, by alternative splicing, two isoforms of a putative pyrazinamidase/nicotinamidase, orthologous to budding yeast Pnc1p, that is required for normal lifespan; PNC-1 is paralogous to Y57G11C.47; because its overexpression increases survival during oxidative stress, PNC-1 may be required for oxidative resistance in vivo; pnc-1(RNAi) animals are abnormally short-lived.
Enables nicotinamidase activity. Involved in nicotinamide metabolic process. Located in cytoplasm; extracellular space; and nucleus. Expressed in several structures, including coelomocyte; epithelial cell; head ganglion; lumbar neurons; and pharyngeal cell.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.