WormBase Tree Display for Gene: WBGene00021351

WBGene00021351 SMap: S_parent: Sequence: Y37E3
  Identity: Version: 2
    Name: CGC_name: eif-2alpha Person_evidence: WBPerson2266
      Sequence_name: Y37E3.10
      Molecular_name: Y37E3.10a
        Y37E3.10a.1
        CE29373
        Y37E3.10a.2
        Y37E3.10b
      Other_name: eIF2alpha Paper_evidence: WBPaper00045601
        CELE_Y37E3.10 Accession_evidence: NDB BX284601
      Public_name: eif-2alpha
    DB_info: Database: AceView gene 1C643
        WormQTL gene WBGene00021351
        WormFlux gene WBGene00021351
        NDB locus_tag CELE_Y37E3.10
        Panther gene CAEEL|WormBase=WBGene00021351|UniProtKB=Q9BKU3
          family PTHR10602
        NCBI gene 171769
        RefSeq protein NR_131351.1
            NM_001381335.2
        TrEMBL UniProtAcc Q9BKU3
        UniProt_GCRP UniProtAcc Q9BKU3
        RNAcentral URSid URS0000730E85
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 09 Jan 2017 15:00:31 WBPerson2970 Name_change: CGC_name: eif-2alpha
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: eif
    Allele (123)
    RNASeq_FPKM (74)
    GO_annotation (11)
    Contained_in_operon: CEOP1036
    Ortholog (37)
    Structured_description: Automated_description: Predicted to enable ribosome binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic 48S preinitiation complex and eukaryotic translation initiation factor 2 complex. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is an ortholog of human EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3265)
  Molecular_info: Corresponding_CDS: Y37E3.10a
    Corresponding_transcript: Y37E3.10b
      Y37E3.10a.1
      Y37E3.10a.2
    Other_sequence (75)
    Associated_feature: WBsf217274
      WBsf217275
  Experimental_info: RNAi_result: WBRNAi00077050 Inferred_automatically: RNAi_primary
      WBRNAi00106640 Inferred_automatically: RNAi_primary
      WBRNAi00023003 Inferred_automatically: RNAi_primary
      WBRNAi00117178 Inferred_automatically: RNAi_primary
      WBRNAi00106717 Inferred_automatically: RNAi_primary
      WBRNAi00055927 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1018707
      Expr1039319
      Expr1159447
      Expr2011249
      Expr2029485
    Antibody: WBAntibody00001402
    Microarray_results (18)
    Expression_cluster (107)
    Interaction (167)
    Anatomy_function: WBbtf1107
      WBbtf1108
  Map_info: Map: I Position: -11.889
    Positive: Positive_clone: Y37E3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027281
    WBPaper00031700
    WBPaper00038491
    WBPaper00045601
    WBPaper00053567
    WBPaper00055090
    WBPaper00063971
    WBPaper00064339
    WBPaper00065116
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene