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WormBase Tree Display for Gene: WBGene00021127

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Name Class

WBGene00021127SMapS_parentSequenceW10C8
Identity (6)
Gene_infoBiotypeSO:0001217
Allele (30)
RNASeq_FPKM (74)
GO_annotation00033786
Ortholog (43)
Paralog (45)
Structured_descriptionAutomated_descriptionEnriched in excretory gland cell; pharyngeal cell; and touch receptor neurons based on tiling array; microarray; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by thirteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Human GSTA1 enables several functions, including glutathione peroxidase activity; glutathione transferase activity; and steroid delta-isomerase activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal; and Glutathione S-transferase, C-terminal domain. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:2841Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4626)
DOID:2394Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4626)
Molecular_infoCorresponding_CDSW10C8.4a
W10C8.4c
W10C8.4d
Corresponding_CDS_historyW10C8.4b:wp96
W10C8.4b:wp245
W10C8.4b:wp274
Corresponding_transcriptW10C8.4a.1
W10C8.4c.1
W10C8.4d.1
Other_sequenceEX553359.1
Acan_isotig15788
FD515160.1
Tcol_isotig12548
CSC01285_1
ACC11024_1
Associated_featureWBsf648990
WBsf983003
WBsf983004
WBsf219069
Experimental_infoRNAi_resultWBRNAi00077233Inferred_automaticallyRNAi_primary
WBRNAi00036427Inferred_automaticallyRNAi_primary
WBRNAi00004464Inferred_automaticallyRNAi_primary
WBRNAi00055081Inferred_automaticallyRNAi_primary
Expr_patternExpr1025421
Expr1158617
Expr2006906
Expr2025133
Microarray_results (21)
Expression_cluster (146)
Interaction (29)
Map_infoPositivePositive_cloneW10C8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionI-5.31164
MethodGene