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WormBase Tree Display for Gene: WBGene00021127

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Name Class

WBGene00021127SMapS_parentSequenceW10C8
IdentityVersion1
NameSequence_nameW10C8.4
Molecular_nameW10C8.4a
W10C8.4a.1
CE30703
W10C8.4c
CE50143
W10C8.4d
CE50184
W10C8.4c.1
W10C8.4d.1
Other_nameCELE_W10C8.4Accession_evidenceNDBBX284601
Public_nameW10C8.4
DB_infoDatabaseAceViewgene1D420
WormQTLgeneWBGene00021127
WormFluxgeneWBGene00021127
NDBlocus_tagCELE_W10C8.4
PanthergeneCAEEL|WormBase=WBGene00021127|UniProtKB=O45010
familyPTHR11571
NCBIgene189332
RefSeqproteinNM_001313518.3
NM_058655.6
NM_001313517.3
TrEMBLUniProtAccA0A0K3AWN2
A0A0K3AUA9
O45010
UniProt_GCRPUniProtAccO45010
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:04WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (30)
RNASeq_FPKM (74)
GO_annotation00033786
Ortholog (43)
Paralog (45)
Structured_descriptionAutomated_descriptionEnriched in excretory gland cell; pharyngeal cell; and touch receptor neurons based on tiling array; microarray; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by thirteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Human GSTA1 enables several functions, including glutathione peroxidase activity; glutathione transferase activity; and steroid delta-isomerase activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal; and Glutathione S-transferase, C-terminal domain. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:2841Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4626)
DOID:2394Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4626)
Molecular_infoCorresponding_CDSW10C8.4a
W10C8.4c
W10C8.4d
Corresponding_CDS_historyW10C8.4b:wp96
W10C8.4b:wp245
W10C8.4b:wp274
Corresponding_transcriptW10C8.4a.1
W10C8.4c.1
W10C8.4d.1
Other_sequenceEX553359.1
Acan_isotig15788
FD515160.1
Tcol_isotig12548
CSC01285_1
ACC11024_1
Associated_featureWBsf648990
WBsf983003
WBsf983004
WBsf219069
Experimental_infoRNAi_resultWBRNAi00077233Inferred_automaticallyRNAi_primary
WBRNAi00036427Inferred_automaticallyRNAi_primary
WBRNAi00004464Inferred_automaticallyRNAi_primary
WBRNAi00055081Inferred_automaticallyRNAi_primary
Expr_patternExpr1025421
Expr1158617
Expr2006906
Expr2025133
Microarray_results (21)
Expression_clusterWBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_embryo_enriched
WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
WBPaper00040420:ALM_PLM_enriched
WBPaper00042194:nhr-114(RNAi)_downregulated
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
WBPaper00042561:smgl-1(RNAi)_upregulated
WBPaper00044037:eat-2_upregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00044743:wdr-23_neuron_upregulated
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045316:prg-1_upregulated_L4
WBPaper00045420:fertilization_upregulated_transcript
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
WBPaper00046805:csr-1(RNAi)_upregulated_Set1
WBPaper00050080:rbr-2(tm3141)_downregulated
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00051245:cytoplasm_specific
WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
WBPaper00051245:pharyngeal-muscle_specific
WBPaper00051352:Long-Term-Association-Memory_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053402:cco-1(RNAi)_upregulated
WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88)
WBPaper00053771:up_at_dpy-7(e88)
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055013:spt-16(RNAi)_upregulated
WBPaper00055354:eat-2(ad1116)_upregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055354:Rifampicin-Psora_upregulated
WBPaper00055386:daf-2(e1370)_upregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00057068:Cadmium_upregulated
WBPaper00057068:numr-1(RNAi)_downregulated_Cadmium
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058948:PA14_downregulated
WBPaper00059117:B.subtilis_upregulated
WBPaper00059253:sucrose_stearic-acid_upregulated
WBPaper00059253:sucrose_upregulated
WBPaper00059754:E.faecalis_OG1RF_upregulated
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060661:sensory-neuron_depleted
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:Excretory_gland
WBPaper00061340:mc2
WBPaper00061340:pm1_pm2
WBPaper00061340:pm3_pm4_pm5
WBPaper00061340:pm6
WBPaper00061340:pm7
WBPaper00061340:pm8
WBPaper00061527:T20B5.2-W07B8.3_16060
WBPaper00061818:ELKS-1_interacting
WBPaper00061995:mter-4(syb3662syb3403)_downregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062440:crh-1(n3315)_downregulated
WBPaper00062440:crh-1(syb385)_downregulated
WBPaper00064005:starvation_downregulated_N2_protein
WBPaper00064494:postdauer_upregulated_AWA
WBPaper00064637:cox-5B(RNAi)_upregulated
WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
WBPaper00065581:hpk-1(pk1393)_upregulated
WBPaper00065623:76
WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
WBPaper00065749:Heat-Shock_downregulated_N2
WBPaper00065823:pmk-1(km25)_upregulated
WBPaper00065841:9_0
WBPaper00065841:9_1
WBPaper00065841:9_2
WBPaper00065841:24_0
WBPaper00065841:24_1
WBPaper00065841:26_0
WBPaper00065841:26_1
WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066110:Doxorubicin_upregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_upregulated
cgc4489_group_12
WBPaper00027342:alpha-Synuclein(A53T)_downregulated
WBPaper00031003:hlh_1_enriched
WBPaper00032948:FedUp
WBPaper00036123:Atrazine_regulated
WBPaper00038172:crh-1null_up_regulated
WBPaper00038172:tax-6null_up_regulated
WBPaper00041174:environmental
WBPaper00041174:environmental_prime
WBPaper00041207:CE_dauer_up
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
WBPaper00047070:DAF-16-dependent_UV_response
WBPaper00047070:N2_starvation_upregulated
WBPaper00047070:N2_UV_upregulated
WBPaper00047070:xpa-1_UV_upregulated
WBPaper00048989:N2_allantoin_downregulated
WBPaper00056330:mrps-5(RNAi)_upregulated
WBPaper00057098:SiO2-nanoparticles_upregulated
InteractionWBInteraction000188037
WBInteraction000216933
WBInteraction000286429
WBInteraction000316641
WBInteraction000326640
WBInteraction000332062
WBInteraction000348837
WBInteraction000365879
WBInteraction000390977
WBInteraction000399324
WBInteraction000399325
WBInteraction000402147
WBInteraction000405052
WBInteraction000409037
WBInteraction000421510
WBInteraction000433300
WBInteraction000445224
WBInteraction000448349
WBInteraction000463118
WBInteraction000465078
WBInteraction000465762
WBInteraction000465776
WBInteraction000466449
WBInteraction000467797
WBInteraction000467834
WBInteraction000468026
WBInteraction000468736
WBInteraction000473465
WBInteraction000578821
Map_infoPositivePositive_cloneW10C8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionI-5.31164
MethodGene