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WormBase Tree Display for Gene: WBGene00021127

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Name Class

WBGene00021127SMapS_parentSequenceW10C8
IdentityVersion1
NameSequence_nameW10C8.4
Molecular_nameW10C8.4a
W10C8.4a.1
CE30703
W10C8.4c
CE50143
W10C8.4d
CE50184
W10C8.4c.1
W10C8.4d.1
Other_nameCELE_W10C8.4Accession_evidenceNDBBX284601
Public_nameW10C8.4
DB_infoDatabaseAceViewgene1D420
WormQTLgeneWBGene00021127
WormFluxgeneWBGene00021127
NDBlocus_tagCELE_W10C8.4
PanthergeneCAEEL|WormBase=WBGene00021127|UniProtKB=O45010
familyPTHR11571
NCBIgene189332
RefSeqproteinNM_001313518.3
NM_058655.6
NM_001313517.3
TrEMBLUniProtAccA0A0K3AWN2
A0A0K3AUA9
O45010
UniProt_GCRPUniProtAccO45010
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:04WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (30)
RNASeq_FPKM (74)
GO_annotation00033786
Ortholog (43)
Paralog (45)
Structured_descriptionAutomated_descriptionEnriched in excretory gland cell; pharyngeal cell; and touch receptor neurons based on tiling array; microarray; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by thirteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Human GSTA1 enables several functions, including glutathione peroxidase activity; glutathione transferase activity; and steroid delta-isomerase activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal; and Glutathione S-transferase, C-terminal domain. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:2841Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4626)
DOID:2394Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4626)
Molecular_infoCorresponding_CDSW10C8.4a
W10C8.4c
W10C8.4d
Corresponding_CDS_historyW10C8.4b:wp96
W10C8.4b:wp245
W10C8.4b:wp274
Corresponding_transcriptW10C8.4a.1
W10C8.4c.1
W10C8.4d.1
Other_sequenceEX553359.1
Acan_isotig15788
FD515160.1
Tcol_isotig12548
CSC01285_1
ACC11024_1
Associated_featureWBsf648990
WBsf983003
WBsf983004
WBsf219069
Experimental_infoRNAi_resultWBRNAi00077233Inferred_automaticallyRNAi_primary
WBRNAi00036427Inferred_automaticallyRNAi_primary
WBRNAi00004464Inferred_automaticallyRNAi_primary
WBRNAi00055081Inferred_automaticallyRNAi_primary
Expr_patternExpr1025421
Expr1158617
Expr2006906
Expr2025133
Microarray_results (21)
Expression_clusterWBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_embryo_enriched
WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
WBPaper00040420:ALM_PLM_enriched
WBPaper00042194:nhr-114(RNAi)_downregulated
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
WBPaper00042561:smgl-1(RNAi)_upregulated
WBPaper00044037:eat-2_upregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00044743:wdr-23_neuron_upregulated
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045316:prg-1_upregulated_L4
WBPaper00045420:fertilization_upregulated_transcript
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
WBPaper00046805:csr-1(RNAi)_upregulated_Set1
WBPaper00050080:rbr-2(tm3141)_downregulated
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00051245:cytoplasm_specific
WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
WBPaper00051245:pharyngeal-muscle_specific
WBPaper00051352:Long-Term-Association-Memory_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(ot269)_downregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053402:cco-1(RNAi)_upregulated
WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88)
WBPaper00053771:up_at_dpy-7(e88)
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055013:spt-16(RNAi)_upregulated
WBPaper00055354:eat-2(ad1116)_upregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055354:Rifampicin-Psora_upregulated
WBPaper00055386:daf-2(e1370)_upregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00057068:Cadmium_upregulated
WBPaper00057068:numr-1(RNAi)_downregulated_Cadmium
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058948:PA14_downregulated
WBPaper00059117:B.subtilis_upregulated
WBPaper00059253:sucrose_stearic-acid_upregulated
WBPaper00059253:sucrose_upregulated
WBPaper00059754:E.faecalis_OG1RF_upregulated
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060661:sensory-neuron_depleted
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:Excretory_gland
WBPaper00061340:mc2
WBPaper00061340:pm1_pm2
WBPaper00061340:pm3_pm4_pm5
WBPaper00061340:pm6
WBPaper00061340:pm7
WBPaper00061340:pm8
WBPaper00061527:T20B5.2-W07B8.3_16060
WBPaper00061818:ELKS-1_interacting
WBPaper00061995:mter-4(syb3662syb3403)_downregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062440:crh-1(n3315)_downregulated
WBPaper00062440:crh-1(syb385)_downregulated
WBPaper00064005:starvation_downregulated_N2_protein
WBPaper00064494:postdauer_upregulated_AWA
WBPaper00064637:cox-5B(RNAi)_upregulated
WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
WBPaper00065581:hpk-1(pk1393)_upregulated
WBPaper00065623:76
WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
WBPaper00065749:Heat-Shock_downregulated_N2
WBPaper00065823:pmk-1(km25)_upregulated
WBPaper00065841:9_0
WBPaper00065841:9_1
WBPaper00065841:9_2
WBPaper00065841:24_0
WBPaper00065841:24_1
WBPaper00065841:26_0
WBPaper00065841:26_1
WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066110:Doxorubicin_upregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_upregulated
cgc4489_group_12
WBPaper00027342:alpha-Synuclein(A53T)_downregulated
WBPaper00031003:hlh_1_enriched
WBPaper00032948:FedUp
WBPaper00036123:Atrazine_regulated
WBPaper00038172:crh-1null_up_regulated
WBPaper00038172:tax-6null_up_regulated
WBPaper00041174:environmental
WBPaper00041174:environmental_prime
WBPaper00041207:CE_dauer_up
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
WBPaper00047070:DAF-16-dependent_UV_response
WBPaper00047070:N2_starvation_upregulated
WBPaper00047070:N2_UV_upregulated
WBPaper00047070:xpa-1_UV_upregulated
WBPaper00048989:N2_allantoin_downregulated
WBPaper00056330:mrps-5(RNAi)_upregulated
WBPaper00057098:SiO2-nanoparticles_upregulated
Interaction (29)
Map_infoPositivePositive_cloneW10C8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionI-5.31164
MethodGene