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WormBase Tree Display for Gene: WBGene00021063

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Name Class

WBGene00021063SMapS_parentSequenceW06E11
IdentityVersion2
NameCGC_namesbds-1Person_evidenceWBPerson8131
Sequence_nameW06E11.4
Molecular_name (3)
Other_nameW06E11.cCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_W06E11.4Accession_evidenceNDBBX284603
Public_namesbds-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:04WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
204 Jun 2008 11:48:40WBPerson2970Name_changeCGC_namesbds-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsbds
AlleleWBVar00005801
WBVar01500082
WBVar00277449
WBVar01903300
WBVar01443157
WBVar01700394
WBVar02030118
WBVar02030119
WBVar01769015
WBVar01769016
WBVar01769017
WBVar01498832
WBVar01564166
WBVar01564167
WBVar01564168
WBVar01564169
WBVar02012613
WBVar01271740
WBVar01499792
WBVar01499793
WBVar00266186
WBVar01961589
WBVar00388281
WBVar00388282
WBVar00388283
WBVar01400189
WBVar02156431
WBVar02117602
WBVar01395618
WBVar00798367
WBVar00798368
WBVar00798369
WBVar00798370
WBVar00798371
WBVar00798372
WBVar00798373
WBVar00798374
WBVar00798375
WBVar00798376
WBVar00798377
WBVar02069486
StrainWBStrain00051204
RNASeq_FPKM (74)
GO_annotation00077608
00077609
00077610
00077611
00077612
00077613
00077614
00077615
00125534
00125535
Contained_in_operonCEOP3028
Ortholog (36)
Structured_descriptionConcise_descriptionW06E11.4 encodes an ortholog of human SBDS (OMIM:607444, mutated in Shwachman-Bodian-Diamond syndrome) and S. cerevisiae Sdo1p, that is required for the extended lifespan of daf-2(e1370) mutants; W06E11.4 is expressed ubiquitously (or nearly so) in somatic larval and adult tissues; by orthology with yeast Sdo1p, W06E11.4 is predicted to be a nucleolar protein required for maturation of 60S ribosomal subunits; W06E11.4 shares an operon with tag-266 and T19C3.7.Paper_evidenceWBPaper00028829
WBPaper00028832
WBPaper00028833
WBPaper00028836
WBPaper00031212
WBPaper00032020
Curator_confirmedWBPerson567
Date_last_updated24 Jul 2008 00:00:00
Automated_descriptionPredicted to be involved in cytosolic ribosome assembly. Predicted to be located in cytoplasm; nuclear lumen; and spindle. Human ortholog(s) of this gene implicated in Shwachman-Diamond syndrome and aplastic anemia. Is an ortholog of human SBDS (SBDS ribosome maturation factor).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:12449Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19440)
DOID:0060479Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19440)
Molecular_infoCorresponding_CDSW06E11.4
Corresponding_transcriptW06E11.4.1
Other_sequence (91)
Associated_featureWBsf226118
WBsf226119
Experimental_infoRNAi_result (12)
Expr_patternExpr1013363
Expr1039189
Expr1158436
Expr2015610
Expr2033845
Drives_constructWBCnstr00024700
Construct_productWBCnstr00024700
Microarray_results (19)
Expression_cluster (115)
Interaction (47)
Map_infoMapIIIPosition-26.4304Error0.009723
PositivePositive_cloneW06E11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00030887
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene