WormBase Tree Display for Gene: WBGene00020788
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| WBGene00020788 | SMap | S_parent | Sequence | T25B6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | nep-22 | Person_evidence | WBPerson260 | |||||
| Sequence_name | T25B6.2 | ||||||||
| Molecular_name | T25B6.2 | ||||||||
| T25B6.2.1 | |||||||||
| CE14174 | |||||||||
| Other_name | CELE_T25B6.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | nep-22 | ||||||||
| DB_info | Database | AceView | gene | XJ655 | |||||
| WormQTL | gene | WBGene00020788 | |||||||
| WormFlux | gene | WBGene00020788 | |||||||
| NDB | locus_tag | CELE_T25B6.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00020788|UniProtKB=Q22763 | |||||||
| family | PTHR11733 | ||||||||
| NCBI | gene | 181144 | |||||||
| RefSeq | protein | NM_077127.5 | |||||||
| TREEFAM | TREEFAM_ID | TF318791 | |||||||
| TrEMBL | UniProtAcc | Q22763 | |||||||
| UniProt_GCRP | UniProtAcc | Q22763 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 10 Feb 2012 15:49:10 | WBPerson2970 | Name_change | CGC_name | nep-22 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nep | ||||||||
| Allele | WBVar00094414 | Inferred_automatically | From strain object: RB2463 | ||||||
| WBVar02139787 | |||||||||
| WBVar02056550 | |||||||||
| WBVar01487391 | |||||||||
| WBVar01171515 | |||||||||
| WBVar01171516 | |||||||||
| WBVar01171517 | |||||||||
| WBVar01171518 | |||||||||
| WBVar01171519 | |||||||||
| WBVar01171520 | |||||||||
| WBVar01171521 | |||||||||
| WBVar01171522 | |||||||||
| WBVar01171523 | |||||||||
| WBVar01171524 | |||||||||
| WBVar01171525 | |||||||||
| WBVar01171526 | |||||||||
| WBVar01171527 | |||||||||
| WBVar01171528 | |||||||||
| WBVar01171529 | |||||||||
| WBVar01171530 | |||||||||
| WBVar01171531 | |||||||||
| WBVar01171532 | |||||||||
| WBVar01171533 | |||||||||
| WBVar01171534 | |||||||||
| WBVar01171535 | |||||||||
| WBVar01171536 | |||||||||
| WBVar01171537 | |||||||||
| WBVar01171538 | |||||||||
| WBVar02065447 | |||||||||
| WBVar02150744 | |||||||||
| WBVar01894627 | |||||||||
| WBVar01602071 | |||||||||
| WBVar01602072 | |||||||||
| WBVar00081735 | |||||||||
| WBVar00081736 | |||||||||
| WBVar01499963 | |||||||||
| WBVar02086823 | |||||||||
| WBVar01550827 | |||||||||
| WBVar01550828 | |||||||||
| WBVar02125399 | |||||||||
| WBVar01473763 | |||||||||
| WBVar01886528 | |||||||||
| WBVar01886529 | |||||||||
| WBVar01886530 | |||||||||
| WBVar01886531 | |||||||||
| WBVar01886532 | |||||||||
| WBVar01499642 | |||||||||
| WBVar01498722 | |||||||||
| WBVar00511955 | |||||||||
| WBVar00511956 | |||||||||
| WBVar00511957 | |||||||||
| WBVar01782545 | |||||||||
| WBVar00511958 | |||||||||
| WBVar01782546 | |||||||||
| WBVar00511959 | |||||||||
| WBVar00511960 | |||||||||
| WBVar00511961 | |||||||||
| WBVar00511962 | |||||||||
| WBVar00511963 | |||||||||
| WBVar01981155 | |||||||||
| WBVar01497108 | |||||||||
| WBVar01849536 | |||||||||
| WBVar01849537 | |||||||||
| WBVar01849538 | |||||||||
| WBVar01849539 | |||||||||
| WBVar01491414 | |||||||||
| WBVar01849540 | |||||||||
| WBVar01498960 | |||||||||
| WBVar01500067 | |||||||||
| Strain | WBStrain00033138 | ||||||||
| WBStrain00037406 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (31) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | nep-22 encodes two isoforms of a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; NEP-22 is orthologous to Ac-mep-1, a gut luminal neprilysin which is specifically expressed in the adult life stage of Ancylostoma caninum hookworms, and whose protein product is localized to the microvilli of the gastrointestinal tract, suggesting a role in digestion. | Paper_evidence | WBPaper00004584 | |||||
| WBPaper00012962 | |||||||||
| WBPaper00013276 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 27 Mar 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Located in membrane raft. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T25B6.2 | |||||||
| Corresponding_CDS_history | T25B6.2a:wp142 | ||||||||
| T25B6.2b:wp142 | |||||||||
| Corresponding_transcript | T25B6.2.1 | ||||||||
| Other_sequence (102) | |||||||||
| Associated_feature | WBsf648394 | ||||||||
| WBsf236116 | |||||||||
| WBsf236117 | |||||||||
| WBsf236118 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00054097 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00000575 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00035945 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089168 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00019187 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1019959 | ||||||||
| Expr1039054 | |||||||||
| Expr1157641 | |||||||||
| Expr2013967 | |||||||||
| Expr2032206 | |||||||||
| Drives_construct | WBCnstr00024887 | ||||||||
| Construct_product | WBCnstr00024887 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (260) | |||||||||
| Interaction (40) | |||||||||
| Map_info | Map | X | Position | 0.573562 | |||||
| Positive | Positive_clone | T25B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00011415 | ||||||||
| WBPaper00011735 | |||||||||
| WBPaper00029046 | |||||||||
| WBPaper00037777 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
