WormBase Tree Display for Gene: WBGene00020696
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| WBGene00020696 | SMap | S_parent | Sequence | CHROMOSOME_V | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pygl-1 | Paper_evidence | WBPaper00051388 | |||||
| Person_evidence | WBPerson20822 | ||||||||
| Sequence_name | T22F3.3 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_T22F3.3 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | pygl-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 01 Aug 2017 12:58:54 | WBPerson2970 | Name_change | CGC_name | pygl-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pygl | ||||||||
| Allele (119) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (53) | |||||||||
| Structured_description | Automated_description | Predicted to enable glycogen phosphorylase activity and pyridoxal phosphate binding activity. Predicted to be involved in glycogen catabolic process. Predicted to be located in cytoplasm. Expressed in germ line. Human ortholog(s) of this gene implicated in glycogen storage disease V; glycogen storage disease VI; and lactic acidosis. Is an ortholog of human PYGM (glycogen phosphorylase, muscle associated). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:2746 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9726) | ||||
| DOID:2754 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9725) | ||||||
| DOID:2747 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9725) | ||||||
| DOID:3650 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9725) | ||||||
| Disease_relevance | The human glycogen phosphorylase isozymes of brain (PYGB), liver (PGYL) and muscle (PYGM), remove glycosyl units from the terminal branches of glycogen through phosphorolysis, forming glucose 1-phosphate; PYGL, when mutated leads to Glycogen storage disease VI, and mutations in PYGM are associated with McArdle disease or Glycogen storage type V disease. | Homo sapiens | Accession_evidence | OMIM | 232700 | ||||
| 232600 | |||||||||
| 138550 | |||||||||
| 613741 | |||||||||
| 608455 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 25 Jun 2012 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T22F3.3a | |||||||
| T22F3.3b | |||||||||
| T22F3.3c | |||||||||
| T22F3.3d | |||||||||
| Corresponding_transcript | T22F3.3a.1 | ||||||||
| T22F3.3b.1 | |||||||||
| T22F3.3c.1 | |||||||||
| T22F3.3d.1 | |||||||||
| Other_sequence (181) | |||||||||
| Associated_feature (18) | |||||||||
| Experimental_info | RNAi_result (14) | ||||||||
| Expr_pattern | Expr4060 | ||||||||
| Expr1013095 | |||||||||
| Expr1039015 | |||||||||
| Expr1157395 | |||||||||
| Expr2006375 | |||||||||
| Expr2024595 | |||||||||
| Drives_construct | WBCnstr00024952 | ||||||||
| Construct_product | WBCnstr00024952 | ||||||||
| Microarray_results (32) | |||||||||
| Expression_cluster (189) | |||||||||
| Interaction (79) | |||||||||
| Map_info | Map | V | Position | -8.62342 | |||||
| Positive | Positive_clone | T22F3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
